A model of human cardiovascular system containing a loop for the autonomic control of mean blood pressure
- Authors: Karavaev A.S.1,2, Ishbulatov Y.M.1, Kiselev A.R.1,3,4, Ponomarenko V.I.1,2, Prokhorov M.D.2, Mironov S.A.5, Shvartz V.A.4, Gridnev V.I.1,3, Bezruchko B.P.1,2
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Affiliations:
- Chernyshevsky Saratov State University
- Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
- Razumovsky Saratov State Medical University
- Bakoulev Scientific Center for Cardiovascular Surgery
- Central Military Hospital
- Issue: Vol 43, No 1 (2017)
- Pages: 61-70
- Section: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/177092
- DOI: https://doi.org/10.1134/S0362119716060098
- ID: 177092
Cite item
Abstract
We propose a model for the human cardiovascular system that describes the cardiac cycle, the autonomic regulation of heart and vessels, the baroreflex, and the formation of blood pressure. The model also allows for the influence of respiration on these processes. It has been found that an allowance for nonlinearity and insertion of a loop for the autonomic control of mean blood pressure (having the form of selfoscillating time-delay system) enables obtaining model signals with statistical and spectral characteristics that are qualitatively and quantitatively similar to those for experimental signals. The model reproduces the phenomenon of synchronization of the loop for mean blood pressure regulation with a basic frequency of approximately 10 s by the signal of respiration.
About the authors
A. S. Karavaev
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Russian Federation, Saratov, 410012; Saratov, 410019
Yu. M. Ishbulatov
Chernyshevsky Saratov State University
Email: antonkis@list.ru
Russian Federation, Saratov, 410012
A. R. Kiselev
Chernyshevsky Saratov State University; Razumovsky Saratov State Medical University; Bakoulev Scientific Center for Cardiovascular Surgery
Author for correspondence.
Email: antonkis@list.ru
Russian Federation, Saratov, 410012; Saratov, 410012; Moscow, 121552
V. I. Ponomarenko
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Russian Federation, Saratov, 410012; Saratov, 410019
M. D. Prokhorov
Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Russian Federation, Saratov, 410019
S. A. Mironov
Central Military Hospital
Email: antonkis@list.ru
Russian Federation, Moscow, 123182
V. A. Shvartz
Bakoulev Scientific Center for Cardiovascular Surgery
Email: antonkis@list.ru
Russian Federation, Moscow, 121552
V. I. Gridnev
Chernyshevsky Saratov State University; Razumovsky Saratov State Medical University
Email: antonkis@list.ru
Russian Federation, Saratov, 410012; Saratov, 410012
B. P. Bezruchko
Chernyshevsky Saratov State University; Saratov Branch, Kotelnikov Institute of Radio Engineering and Electronics
Email: antonkis@list.ru
Russian Federation, Saratov, 410012; Saratov, 410019