Toll-Like Receptors in Peripheral Blood Cells of Cosmonauts after Long-term Missions on Board the International Space Station
- Авторлар: Berendeeva T.1, Ponomarev S.1, Antropova E.1, Rykova M.1
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Мекемелер:
- Institute for Biomedical Problems
- Шығарылым: Том 43, № 7 (2017)
- Беттер: 802-807
- Бөлім: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/177397
- DOI: https://doi.org/10.1134/S0362119717070039
- ID: 177397
Дәйексөз келтіру
Аннотация
Studies of Toll-like receptors (TLR) in 20 cosmonauts, members of long-term (124- to 199-day) missions on board the International Space Station showed changes in the relative and absolute counts of peripheral blood monocytes with TLR2, TLR4, and TLR6 on their surface, expression of genes TLR2 and TLR6, as well as genes of molecules involved in the TLR signaling pathway and TLR-related NF-κB-, JNK/p38- and IRF pathways on the day of return to Earth. The observed changes displayed individual variability.
Негізгі сөздер
Авторлар туралы
T. Berendeeva
Institute for Biomedical Problems
Хат алмасуға жауапты Автор.
Email: tberendeeva@mail.ru
Ресей, Moscow, 123007
S. Ponomarev
Institute for Biomedical Problems
Email: tberendeeva@mail.ru
Ресей, Moscow, 123007
E. Antropova
Institute for Biomedical Problems
Email: tberendeeva@mail.ru
Ресей, Moscow, 123007
M. Rykova
Institute for Biomedical Problems
Email: tberendeeva@mail.ru
Ресей, Moscow, 123007