Progressive Multifocal Leukoencephalopathy as a Complication of Disease-modifying Treatment of Multiple Sclerosis
- Авторлар: Zakharova M.1, Lysogorskaia E.1, Ivanova M.1, Kochergin I.1, Korzhova Y.1
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Мекемелер:
- Research Center of Neurology
- Шығарылым: Том 45, № 8 (2019)
- Беттер: 863-868
- Бөлім: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/178498
- DOI: https://doi.org/10.1134/S0362119719080097
- ID: 178498
Дәйексөз келтіру
Аннотация
The review provides modern understanding of the pathogenesis of progressive multifocal leukoencephalopathy (PML), a severe and potentially fatal form of multiple-lesion disorder of the brain white matter. Information about the frequency of its development in patients with disease-modifying treatment of multiple sclerosis is analyzed. The algorithms of optimization of PML risks in this category of patients with multiple sclerosis are described in detail. Summarized are the data on most significant PML biomarkers, the search for which is currently under way in many centers across the world. The first case of PML in Russia is briefly described.
Авторлар туралы
M. Zakharova
Research Center of Neurology
Email: lysogorskaya@neurology.ru
Ресей, Moscow
E. Lysogorskaia
Research Center of Neurology
Хат алмасуға жауапты Автор.
Email: lysogorskaya@neurology.ru
Ресей, Moscow
M. Ivanova
Research Center of Neurology
Email: lysogorskaya@neurology.ru
Ресей, Moscow
I. Kochergin
Research Center of Neurology
Email: lysogorskaya@neurology.ru
Ресей, Moscow
Y. Korzhova
Research Center of Neurology
Email: lysogorskaya@neurology.ru
Ресей, Moscow