Structural and Functional Basis of Chronic Disorders of Consciousnes
- 作者: Piradov M.1, Iazeva E.2, Morozova S.3, Kremneva E.3, Poydasheva A.4, Sinitsyn D.4, Ryabinkina Y.2, Chervyakov A.4, Sergeev D.2, Suponeva N.5, Legostaeva L.4
-
隶属关系:
- Research Center of Neurology
- Department of Intensive Care, Research Center of Neurology
- Department of Neuroimaging, Research Center of Neurology
- Neurorehabilitation Department, Research Center of Neurology
- Head of Neurorehabilitation Department, Research Center of Neurology
- 期: 卷 45, 编号 8 (2019)
- 页面: 811-820
- 栏目: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/178481
- DOI: https://doi.org/10.1134/S0362119719080073
- ID: 178481
如何引用文章
详细
The problem of chronic disorders of consciousness (DOC) remains challenging due to increasing number of these patients and limited therapeutic options. Novel diagnostic approaches provided us with valuable insights into the mechanisms of DOC, such as structural and/or functional disconnection of elements of brain networks that are essential for information processing. Depending on the modality of the study, it may be represented as low-frequency EEG patterns, global or regional decrease of cortical metabolism on PET scanning, abnormal connectivity structural or functional MRI, or low-differentiated/disintegrated TMS-EEG responses. Deeper knowledge of nature of abnormalities underlying chronic DOC may improve accuracy of diagnosis and efficacy of treatment interventions, as well as bring us somewhat closer to the understanding the phenomenon of consciousness.
作者简介
M. Piradov
Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
E. Iazeva
Department of Intensive Care, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
S. Morozova
Department of Neuroimaging, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
E. Kremneva
Department of Neuroimaging, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
A. Poydasheva
Neurorehabilitation Department, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
D. Sinitsyn
Neurorehabilitation Department, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
Yu. Ryabinkina
Department of Intensive Care, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
A. Chervyakov
Neurorehabilitation Department, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
D. Sergeev
Department of Intensive Care, Research Center of Neurology
编辑信件的主要联系方式.
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
N. Suponeva
Head of Neurorehabilitation Department, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow
L. Legostaeva
Neurorehabilitation Department, Research Center of Neurology
Email: dmsergeev@yandex.ru
俄罗斯联邦, Moscow