Email this article Search for Blood Proteome Proteins Involved in the Regulation of Bone Remodeling in Astronauts
- Authors: Pastushkova L.K.1, Goncharova A.G.1, Vasilyeva G.Y.1, Tagirova S.K.1,2, Kashirina D.N.1, Sayk O.V.3, Rittweger J.4, Larina I.M.1
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Affiliations:
- Institute of Biomedical Problems, Russian Academy of Sciences
- City Clinical Hospital no. 29 named after N.E. Bauman, Moscow Department of Health
- Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences
- German Aerospace Center, Institute of Aerospace Medicine
- Issue: Vol 45, No 5 (2019)
- Pages: 536-542
- Section: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/178306
- DOI: https://doi.org/10.1134/S0362119719050128
- ID: 178306
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Abstract
On the basis of proteomics, modern data on the features of bone remodeling in astronauts after long-term space flights are presented. We describe the regulatory proteins of the blood proteome that are significantly associated with bone remodeling processes. By analyzing large amounts of data, we for the first time determined associations of signaling proteins that are process regulators characterizing new steps of bone remodeling in astronauts during the acute period of readaptation after landing.
About the authors
L. Kh. Pastushkova
Institute of Biomedical Problems, Russian Academy of Sciences
Email: galvassilieva@mail.ru
Russian Federation, Moscow
A. G. Goncharova
Institute of Biomedical Problems, Russian Academy of Sciences
Email: galvassilieva@mail.ru
Russian Federation, Moscow
G. Yu. Vasilyeva
Institute of Biomedical Problems, Russian Academy of Sciences
Author for correspondence.
Email: galvassilieva@mail.ru
Russian Federation, Moscow
S. K. Tagirova
Institute of Biomedical Problems, Russian Academy of Sciences; City Clinical Hospital no. 29 named after N.E. Bauman, Moscow Department of Health
Email: galvassilieva@mail.ru
Russian Federation, Moscow; Moscow
D. N. Kashirina
Institute of Biomedical Problems, Russian Academy of Sciences
Email: galvassilieva@mail.ru
Russian Federation, Moscow
O. V. Sayk
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences
Email: galvassilieva@mail.ru
Russian Federation, Novosibirsk
J. Rittweger
German Aerospace Center, Institute of Aerospace Medicine
Email: galvassilieva@mail.ru
Germany, Cologne
I. M. Larina
Institute of Biomedical Problems, Russian Academy of Sciences
Email: galvassilieva@mail.ru
Russian Federation, Moscow
