Early Onset of Muscle Atrophy in Women with Chronic Alcoholic Myopathy

O. E. Zinovyeva; N. D. Samhaeva; D. O. Kazakov; O. V. Turtikova; A. M. Nosovskii; B. S. Shenkman; T. L. Nemirovskaya

doi:10.1134/S0362119718030179

Early Onset of Muscle Atrophy in Women with Chronic Alcoholic Myopathy

作者: Zinovyeva O.E.¹, Samhaeva N.D.¹, Kazakov D.O.², Turtikova O.V.³, Nosovskii A.M.³, Shenkman B.S.³, Nemirovskaya T.L.³^,4
隶属关系:
1. Sechenov First State Medical University
2. Veltishchev Clinical Research Institute for Pediatry
3. Institute of Biomedical Problems
4. Moscow State University
期: 卷 44, 编号 3 (2018)
页面: 356-359
栏目: Short Communications
URL: https://journals.rcsi.science/0362-1197/article/view/177670
DOI: https://doi.org/10.1134/S0362119718030179
ID: 177670

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This is the first study to observe a 25% atrophy of m. vastus lateralis and a decrease in the size of type I and II muscle fibers (by 35 and 44%, respectively) using magnetic resonance imaging (MRI) in women after five to seven years of alcohol intoxication. The decrease in muscle volume is due to the predominant destruction of contractile apparatus as compared with other components.