Early Onset of Muscle Atrophy in Women with Chronic Alcoholic Myopathy

O. E. Zinovyeva; N. D. Samhaeva; D. O. Kazakov; O. V. Turtikova; A. M. Nosovskii; B. S. Shenkman; T. L. Nemirovskaya

doi:10.1134/S0362119718030179

Early Onset of Muscle Atrophy in Women with Chronic Alcoholic Myopathy

Authors: Zinovyeva O.E.¹, Samhaeva N.D.¹, Kazakov D.O.², Turtikova O.V.³, Nosovskii A.M.³, Shenkman B.S.³, Nemirovskaya T.L.³^,4
Affiliations:
1. Sechenov First State Medical University
2. Veltishchev Clinical Research Institute for Pediatry
3. Institute of Biomedical Problems
4. Moscow State University
Issue: Vol 44, No 3 (2018)
Pages: 356-359
Section: Short Communications
URL: https://journals.rcsi.science/0362-1197/article/view/177670
DOI: https://doi.org/10.1134/S0362119718030179
ID: 177670

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Abstract

This is the first study to observe a 25% atrophy of m. vastus lateralis and a decrease in the size of type I and II muscle fibers (by 35 and 44%, respectively) using magnetic resonance imaging (MRI) in women after five to seven years of alcohol intoxication. The decrease in muscle volume is due to the predominant destruction of contractile apparatus as compared with other components.