Role of hormones in regulating sodium transporters in the kidney: Modulation of phosphorylation, traffic, and expression
- Authors: Abramicheva P.A.1, Smirnova O.V.1
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Affiliations:
- Moscow State University
- Issue: Vol 43, No 4 (2017)
- Pages: 474-487
- Section: Reviews
- URL: https://journals.rcsi.science/0362-1197/article/view/177251
- DOI: https://doi.org/10.1134/S0362119717040028
- ID: 177251
Cite item
Abstract
The review focuses on the key sodium transporters involved in maintaining water–salt balance in the kidney. The topography of sodium transporters is discussed. Specifics of the hormone-dependent regulation, including phosphorylation, traffic, and expression, are considered for particular transporters. Special attention is paid to direct intracellular regulators of the transporter function. The role that dopamine plays as a natriuretic factor in modulating the function of various transporters is described.
Keywords
About the authors
P. A. Abramicheva
Moscow State University
Author for correspondence.
Email: abramicheva.polina@gmail.com
Russian Federation, Moscow
O. V. Smirnova
Moscow State University
Email: abramicheva.polina@gmail.com
Russian Federation, Moscow