fMRI responses of the brain during active and passive movements in left-handed subjects

详细

The hemodynamic (magnetic resonance imaging, fMRI, 3T) brain responses were studied in 15 left-handed healthy subjects performing active and passive movements of the dominant and non-dominant hands. Group and individual fMRI responses to the motor load were analyzed. It was found that, during the active movements of dominant and non-dominant hands, the main activation cluster appeared in the preand postcentral gyrus of the contralateral hemisphere and which topographically similar during active and passive movements. The activation cluster of greater volume was identified in these areas; the response was more diffused during the non-dominant hand movements in comparison with the dominant hand. During passive movements, the cortical activation clusters of a smaller volume in comparison with the active movements were found, which was expressed most clearly during the performance of non-dominant hand movements and could reflect the weakening of the control from the cortical structures in these conditions.