Biomarkers of cerebral atherosclerosis: The potential for early diagnosis and individual risk prognosis

Abstract

The article deals with the results of a study of “asymptomatic” patients with severe stenosing process in the brachiocephalic arteries (as a model of carotid atherosclerosis), with emphasis on the determination of biochemical markers associated with various stages of atherogenesis. The definition of a group of proatherogenic and atheroprotective biomarkers is suggested and substantiated. The article describes correlations among biomarkers that have a potential etiopathogenic nature, which necessitates further validation of these pathological changes in larger groups of patients.