Physiological mechanisms of simulated purposeful activities of patients with epilepsy

Abstract

In order to look into the physiological mechanisms providing the efficiency of purposeful activity of patients with epilepsy, 102 patients with symptomatic, cryptogenic, and idiopathic forms of this disease were examined. Three clusters of patients were formed using the Gorbov–Shulte performance test. Patients from the low-efficiency cluster were characterized by the lack of the habituation mechanisms in the activity of afferent systems and the mechanisms of motor response; a high level of activity of stress adaptation systems; as well as a higher intrasystemic tension during preparation for purposeful activity compared to patients from the intermediate and high-performance clusters.