Interaction of humic acid salts with drug preparations


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The use of natural polymers that form complexes with drug preparations is promising in the development of drugs of new generation. The possibility of complex formation on the interaction of humic acid salts with papaverine, benzohexonium, and B-group vitamins was demonstrated by calorimetric and potentiometric titration. These interactions can occur between the charged groups of a humic acid macroanion and the positively charged centers of drug molecules. The degree of binding of drug preparations by a natural polymer macromolecule can be determined by the charge and the structure of their molecules.

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S. Khil’ko

Litvinenko Institute of Physical Organic Chemistry and Coal Chemistry

编辑信件的主要联系方式.
Email: sv-hilko@yandex.ru
乌克兰, Donetsk

R. Semenova

Litvinenko Institute of Physical Organic Chemistry and Coal Chemistry

Email: sv-hilko@yandex.ru
乌克兰, Donetsk

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