Application of a response surface method to studying the adsorption of diclofenac sodium from aqueous solutions on activated carbon

Abstract

The adsorption of diclofenac sodium, a commonly used nonsteroidal antiarthritic drug, from aqueous solutions of different concentrations on a carbon adsorbent obtained from coconut shell was studied at different temperatures. Based on the experimental data, a mathematical model was constructed with the use of a mathematical design methodology to describe the dependence of the degree of extraction of diclofenac sodium on experimental conditions. The experimental conditions required for the extraction of no less than 95% diclofenac sodium were determined.