Clinical and prognostic value of NT-proBNP and sST2 biomarkers in elderly patients with heart failure and comorbidities

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Resumo

Chronic heart failure (HF) in elderly patients is characterized by high morbidity and mortality, especially in the presence of comorbidities. The article presents a review of current data on the prognostic value of blood biomarkers — N-terminal pro-brain natriuretic peptide (NT-proBNP) and soluble ST2 receptor (sST2) in elderly comorbid patients with chronic heart failure (CHF). Based on the analysis, the rationale for the combined use of NT-proBNP and sST2 for accurate risk stratification and personalization of therapeutic approaches in elderly patients with CHF and multiple comorbidities is substantiated.

Sobre autores

I. Kochetkova

Burdenko Voronezh State Medical University

Email: iri4217@yandex.ru
Código SPIN: 9933-5015

Candidate of Medical Sciences

Rússia, Voronezh

T. Trofimova

Voronezh State University

Email: iri4217@yandex.ru
ORCID ID: 0009-0006-2818-9134
Código SPIN: 4567-4489

Candidate of Medical Sciences

Rússia, Voronezh

Yu. Lykov

Belgorod State National Research University

Email: iri4217@yandex.ru
ORCID ID: 0000-0002-4185-5502
Código SPIN: 2822-9134
Rússia, Belgorod

A. Kukharchuk

Belgorod State National Research University

Autor responsável pela correspondência
Email: iri4217@yandex.ru
ORCID ID: 0000-0003-3881-2138
Código SPIN: 5035-1117
Rússia, Belgorod

Bibliografia

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