Differential diagnosis of exanthems in infectious mononucleosis (clinical case)
- Authors: Mirolaev M.M.1, Kotlinskaya L.M.2, Burgasova O.A.1, Khodzhibekov R.R.1
-
Affiliations:
- Patrice Lumumba Peoples' Friendship University of Russia
- Russian University of Medicine, Ministry of Health of Russia
- Issue: Vol 35, No 8 (2024)
- Pages: 68-72
- Section: From Practice
- URL: https://journals.rcsi.science/0236-3054/article/view/263634
- DOI: https://doi.org/10.29296/25877305-2024-08-14
- ID: 263634
Cite item
Open Access
Access granted
Subscription Access
Abstract
The article presents a description of a clinical case of infectious mononucleosis with pronounced exanthema in an 18-year-old female patient. The patient's clinical status is analyzed, and a detailed differential diagnosis is conducted with syndrome-similar diseases. The most significant clinical symptoms present in the typical picture of infectious mononucleosis are highlighted. The article discusses the significance of determining antibody avidity for diagnosing the stage of the infectious process. Particular attention is paid to the importance of determining this parameter in pregnant women, where diagnostic accuracy and assessment of disease severity are crucial for making decisions about patient management.
Full Text
##article.viewOnOriginalSite##About the authors
M. M. Mirolaev
Patrice Lumumba Peoples' Friendship University of Russia
Author for correspondence.
Email: mikhailmirolaev@yandex.ru
ORCID iD: 0009-0006-4748-7823
Russian Federation, Moscow
L. M. Kotlinskaya
Russian University of Medicine, Ministry of Health of Russia
Email: mikhailmirolaev@yandex.ru
ORCID iD: 0009-0004-1406-458X
Russian Federation, Moscow
O. A. Burgasova
Patrice Lumumba Peoples' Friendship University of Russia
Email: mikhailmirolaev@yandex.ru
ORCID iD: 0000-0002-5486-0837
MD, Professor
Russian Federation, MoscowR. R. Khodzhibekov
Patrice Lumumba Peoples' Friendship University of Russia
Email: mikhailmirolaev@yandex.ru
ORCID iD: 0000-0001-9703-8459
Candidate of Medical Sciences
Russian Federation, MoscowReferences
- Баранова И.П., Лесина О.Н., Курмаева Д.Ю. Роль инфекционного мононуклеоза в формировании частых заболеваний у детей. Инфекционные болезни. Приложение. 2011; 9 (1) [Baranova I.P., Lesina O.N., Kurmaeva D.Y. Role of infectious mononucleosis in the formation of frequent diseases in children. Infectious diseases. Appl. 2011; 9 (1) (in Russ.)].
- Собчак Д.М. и др. ВЭБ-инфекция (этиология, патогенез, клиника, диагностика, лечение): учебное пособие. Нижний Новгород: Издательство НижГМА, 2010 [Sobchak D.M. et al. VEB-infection (etiology, pathogenesis, clinic, diagnosis, treatment): textbook. Nizhny Novgorod: Nizhny Novgorod State Medical Academy Publishing House, 2010 (in Russ.)].
- Манкевич Р.Н., Романова О.Н., Астапов А.А. Дифференциальная диагностика инфекционных экзантем у детей: учебно-методическое пособие. Минск: БГМУ, 2022; 52 с. [Mankevich R.N., Romanova O.N., Astapov A.A. Differential diagnostics of infectious exanthems in children: teaching manual. Minsk: BSMU, 2022; 52 p. (in Russ.)].
- Клинические рекомендации (протокол лечения) оказания медицинской помощи детям больным инфекционным мононуклеозом. ФГБУ НИИДИ ФМБА России, 2013 [Clinical recommendations (treatment protocol) of medical care for children with infectious mononucleosis. FGBU NIIDI FMBA of Russia, 2013 (in Russ.)].
- Muzumdar S., Rothe M.J., Grant-Kels J.M. The rash with maculopapules and fever in adults. Clin Dermatol. 2019; 37 (2): 109–18. doi: 10.1016/j.clindermatol.2018.12.004
- Dondi A., Parladori R., Mori F. et al. Viral rashes mimicking drug reaction with eosinophilia and systemic symptoms syndrome in children after β-lactams intake: a diagnostic challenge. Eur J Pediatr. 2021; 180 (7): 2327–32. doi: 10.1007/s00431-021-04010-5
- Bodéus M., Feyder S., Goubau P. Avidity of IgG antibodies distinguishes primary from non-primary cytomegalovirus infection in pregnant women. Clin Diagn Virol. 1998; 9 (1): 9–16. doi: 10.1016/s0928-0197(97)10016-2
- Коровина Н.А. и др. Цитомегаловирусная инфекция у детей раннего возраста (клиника, диагностика, современные возможности терапии): руководство для врачей. 2-е изд., перераб. и доп. М.: Медпрактика, 2001 [Korovina N.A. et al. Cytomegalovirus infection in young children (clinic, diagnostics, modern possibilities of therapy): a guide for doctors. 2nd ed., revision and supplement. М.: Medpraktika, 2001 (in Russ.)].
Supplementary files
