Diagnosis of Parkinson's disease by biomedical imaging methods on the example of a clinical case
- Authors: Ryazanov V.V.1, Kutsenko V.P.1, Postanogov R.A1, Seliverstov P.V.2,3, Gafiatulin M.R.1
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Affiliations:
- Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia
- V.A. Almazov National Medical Research Center
- S.M. Kirov Military Medical Academy
- Issue: Vol 34, No 10 (2023)
- Pages: 41-45
- Section: For Diagnosis
- URL: https://journals.rcsi.science/0236-3054/article/view/249527
- DOI: https://doi.org/10.29296/25877305-2023-10-07
- ID: 249527
Cite item
Abstract
Worldwide, Parkinson's disease (PD; primary Parkinsonism) is ahead of other neurological disorders in terms of the growth rate of disability and mortality. Despite significant progress in the study of the etiopathogenesis of PD, early diagnosis is a difficult clinical task. The long latent phase of the disease and the absence of reliable laboratory markers often cause a delay in diagnostic neuroimaging, which, together with the potential unwillingness of the radiologist to see changes characteristic of the neurodegenerative process, leads to untimely diagnosis and, as a consequence, a delay in the appointment of therapy.
This article provides a literary review of generally recognized visualization patterns of the disease in accordance with modern concepts, and also discusses the issues of differential diagnosis of PD with the most common Parkinsonism-plus syndromes. A clinical case of the diagnosis of Parkinson's disease in a 93-year-old patient by structural magnetic resonance imaging is presented.
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##article.viewOnOriginalSite##About the authors
V. V. Ryazanov
Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia
Author for correspondence.
Email: val9126@mail.ru
ORCID iD: 0000-0002-0037-2854
Doctor of Medical Sciences, Associate Professor
Russian Federation, Saint PetersburgV. P. Kutsenko
Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia
Email: val9126@mail.ru
ORCID iD: 0000-0001-9755-1906
Candidate of Medical Sciences
Russian Federation, Saint PetersburgR. A Postanogov
Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia
Email: val9126@mail.ru
ORCID iD: 0000-0002-0523-9411
Russian Federation, Saint Petersburg
P. V. Seliverstov
V.A. Almazov National Medical Research Center; S.M. Kirov Military Medical Academy
Email: val9126@mail.ru
ORCID iD: 0000-0001-5623-4226
Candidate of Medical Sciences
Russian Federation, Saint Petersburg; Saint PetersburgM. R. Gafiatulin
Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia
Email: val9126@mail.ru
ORCID iD: 0000-0002-5224-1717
Russian Federation, Saint Petersburg
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