The characteristics of the hemostatic system in patients with external genital endometriosis
- Authors: Baigalmaa B.1,2, Bitsadze V.O.1, Solopova A.G.1, Blinov D.V.1,3,4, Bykovshchenko G.K.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
- Amgalan Maternal Hospital
- Institute of Preventive and Social Medicine
- F.P. Gaaz Moscow Medical and Social Institute
- Issue: Vol 34, No 5 (2023)
- Pages: 20-25
- Section: Topical Subject
- URL: https://journals.rcsi.science/0236-3054/article/view/143061
- DOI: https://doi.org/10.29296/25877305-2023-05-03
- ID: 143061
Cite item
Abstract
External genital endometriosis (EGE) is a common disease that substantially lowers quality of life in women. EGE is accompanied by chronic pelvic pain in 50% of cases. The role of the hemostatic system, proinflammatory factors, the complement system, and other biomarkers in the pathogenesis of EGE seems interesting. The literature describes an endometriosis-characteristic (local and systemic) condition of local and systemic hypercoagulation, activation of proinflammatory molecules, chemokines, and complement components. It is remarkable that after surgical removal of endometrioid foci, the biochemical and coagulation parameters return to normal. The objective of this review is to summarize the data on the diagnostic and prognostic significance of hemostatic factors, proinflammatory cytokines, cancer markers, the immunological and genetic panels within the framework of EGE.
Full Text
##article.viewOnOriginalSite##About the authors
B. Baigalmaa
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Amgalan Maternal Hospital
Email: blinov2010@googlemail.com
ORCID iD: 0000-0003-0845-7550
Russian Federation, Moscow; Ulan-Bator, Mongolia
V. O. Bitsadze
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: blinov2010@googlemail.com
ORCID iD: 0000-0001-8404-1042
Doctor of Medical Sciences, Professor
Russian Federation, MoscowA. G. Solopova
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-7456-2386
Doctor of Medical Sciences, Professor
Russian Federation, MoscowD. V. Blinov
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Institute of Preventive and Social Medicine; F.P. Gaaz Moscow Medical and Social Institute
Author for correspondence.
Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-3367-9844
Candidate of Medical Sciences
Russian Federation, Moscow; Moscow; MoscowG. K. Bykovshchenko
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: blinov2010@googlemail.com
Russian Federation, Moscow
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