Artificial blood vessels based on Russian fluoropolymers: pilot study
- Autores: Kukartseva O.V.1,2, Buznik V.M.3, Melnik E.Y.1,2, Mishanin A.I.4, Golovkin A.S.4, Bolbasov E.N.1,2
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Afiliações:
- National Research Tomsk Polytechnic University
- Zueva Institute of Atmospheric Optics Siberian Branch, Russian Academy of Sciences
- National Research Tomsk State University
- Almazov National Medical Research Center, Ministry of Health of the Russian Federation
- Edição: Volume 44, Nº 11 (2025)
- Páginas: 67-75
- Seção: Chemical physics of polymeric materials
- URL: https://journals.rcsi.science/0207-401X/article/view/351696
- DOI: https://doi.org/10.7868/S0207401X25110082
- ID: 351696
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Resumo
Artificial blood vessels made from fluoropolymer using electrospinning have high biocompatibility. They have unique combinations of strength, chemical resistance, and open interconnected porosity. This provides favourable conditions for endothelialization. The aim of this study is to investigate the structures and properties of these artificial vessels, formed from Russian fluoropolymer materials such as poly(tetrafluoroethylene), copolymers of vinidene fluoride and tetraflouroethylene, and polyvinylidenefluoroide. Depending on the fluoropolymer used, structural characteristics of vessel walls, surface free energies, strengths, elongations, and interactions with human mesenchymal stem cells are investigated. It has been demonstrated that a copolymer of vinidenedifluoride with tetraflouroethylene represents the most promising material for vessel manufacturing using electrospinning technology.
Sobre autores
O. Kukartseva
National Research Tomsk Polytechnic University; Zueva Institute of Atmospheric Optics Siberian Branch, Russian Academy of Sciences
Email: Ftoroplast@tpu.ru
Tomsk, Russia; Tomsk, Russia
V. Buznik
National Research Tomsk State University
Email: Ftoroplast@tpu.ru
Tomsk, Russia
E. Melnik
National Research Tomsk Polytechnic University; Zueva Institute of Atmospheric Optics Siberian Branch, Russian Academy of Sciences
Email: Ftoroplast@tpu.ru
Tomsk, Russia; Tomsk, Russia
A. Mishanin
Almazov National Medical Research Center, Ministry of Health of the Russian Federation
Email: Ftoroplast@tpu.ru
Saint Petersburg, Russia
A. Golovkin
Almazov National Medical Research Center, Ministry of Health of the Russian Federation
Email: Ftoroplast@tpu.ru
Saint Petersburg, Russia
E. Bolbasov
National Research Tomsk Polytechnic University; Zueva Institute of Atmospheric Optics Siberian Branch, Russian Academy of Sciences
Autor responsável pela correspondência
Email: Ftoroplast@tpu.ru
Tomsk, Russia; Tomsk, Russia
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