Protective Mechanisms of High-Density Lipoproteins on the Cardiovascular System during Physical Exercise

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Abstract

Numerous epidemiological studies have proven an inverse relationship between the content of high-density lipoproteins (HDL) in blood plasma and the risk of developing cardiovascular diseases (CVD) of atherosclerotic genesis. On the other hand, it is well known that regular physical activity is an important component of the treatment of most CVD and prevents the development of atherosclerosis. Thus, the beneficial effect of physical activity on the cardiovascular system can be largely associated with an increase in the level of plasma HDL under these conditions, changes in their composition and functional properties. The purpose of this review is to discuss possible mechanisms of the protective effect of HDL on the cardiovascular system during physical activity.

About the authors

O. N Poteryaeva

Federal Research Center of Fundamental and Translational Medicine, Institute of Biochemistry

Email: Оlga_Poteryaeva@mail.ru
ORCID iD: 0000-0003-1068-2431
Dr. Sci., (Medicine), Leading researcher Novosibirsk, Russian Federation

I. F Usynin

Federal Research Center of Fundamental and Translational Medicine, Institute of Biochemistry

Email: ivan.usynin@yandex.ru
ORCID iD: 0000-0003-1752-9034
Dr. Sci. (Biology), Head of the laboratory Novosibirsk, Russian Federation

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