Motif-Based Prediction of Plant Tubulin Phosphorylation Sites Associated with Calcium-Dependent Protein Kinases in Arabidopsis thaliana
- Авторы: Karpov P.A.1, Novozhylov D.O.1, Isayenkov S.V.1, Blume Y.B.1
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Учреждения:
- Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine
- Выпуск: Том 52, № 6 (2018)
- Страницы: 428-439
- Раздел: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/173995
- DOI: https://doi.org/10.3103/S0095452718060038
- ID: 173995
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Аннотация
New motifs for phosphorylation sites associated with calcium-dependent protein kinases were developed using 494 sites experimentally proved in mammalians. Subsequent motif-based search revealed consensus regions in α-, β-, and γ-tubulin from Arabidopsis thaliana. The analysis of selected candidate sites and comparison of sequences and structures of homological mammalian and plant protein kinases were performed. Bioinformatic analysis reveals Arabidopsis protein kinases CPK20 (At2g38910), CPK21 (AT4G04720), and GRIK2 (At5g60550) as probable contributors of the plant tubulin code.
Об авторах
P. Karpov
Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine
Автор, ответственный за переписку.
Email: karpov@nas.gov.ua
Украина, Kyiv, 04123
D. Novozhylov
Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine
Автор, ответственный за переписку.
Email: novozhylovd@gmail.com
Украина, Kyiv, 04123
S. Isayenkov
Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine
Автор, ответственный за переписку.
Email: stan.isayenkov@gmail.com
Украина, Kyiv, 04123
Ya. Blume
Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine
Автор, ответственный за переписку.
Email: cellbio@cellbio.freenet.viaduk.net
Украина, Kyiv, 04123
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