Cytokine profiles in mice tissues after irradiation of the thymus projection area with femtosecond laser
- Authors: Kanevskyi V.A.1, Pushkarev V.M.1
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Affiliations:
- Komisarenko Institute of Endocrinology and Metabolism
- Issue: Vol 51, No 6 (2017)
- Pages: 462-469
- Section: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/173773
- DOI: https://doi.org/10.3103/S0095452717060044
- ID: 173773
Cite item
Abstract
The effects of pulsed femtosecond laser irradiation in the near ultraviolet region on the levels of cytokines in the thymus, blood, and skin of irradiated mice have been studied. Irradiation of the thymus projection area with low-intensity laser radiation in the near UV region of the spectrum showed significant changes in cytokine levels in the skin and thymus and, to a lesser extent, in the blood of irradiated mice. Laser irradiation with a power density of 20 mW/cm2 affects the cytokine profile in the thymus: IFN-γ, IL-3, IL-4, IL-5, eotaxin, GM-CSF, and chemokine KC–factors that can affect differentiation and proliferation of the cells of the immune system in the gland. Conclusions: It is assumed that changes in the expression of cytokines in the thymus after laser irradiation are explained by the rearrangement of biochemical processes possibly associated with the maturation of cells in the gland.
Keywords
About the authors
V. A. Kanevskyi
Komisarenko Institute of Endocrinology and Metabolism
Email: pushkarev.vm@gmail.com
Ukraine, Kyiv
V. M. Pushkarev
Komisarenko Institute of Endocrinology and Metabolism
Author for correspondence.
Email: pushkarev.vm@gmail.com
Ukraine, Kyiv