Мақаланы E-mail арқылы жіберу Antiarrhythmic Activity of the Flavonoid Fraction of Plantago Major L. Extract
- Авторлар: Khushmatov S.S.1, Makhmudov R.R.1
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Мекемелер:
- A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
- Шығарылым: Том 52, № 12 (2019)
- Беттер: 992-995
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245572
- DOI: https://doi.org/10.1007/s11094-019-01939-8
- ID: 245572
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Аннотация
Antiarrhythmic activity of the flavonoid fraction of Plantago major L. extract (0.05 mg/mL) was studied. The studied fractions were found to lower the frequency of rat cardiac papillary muscle contractions with aconitine-induced (1 μM) arrythmia in vitro. An analysis of literature and experimental data suggested that the antiarrhythmic effects of the studied flavonoid fractions may have been related to functional modulation of Na+- and Ca2+-channels in cardiomyocytes.
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Авторлар туралы
Sh. Khushmatov
A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
Хат алмасуға жауапты Автор.
Email: Khushmatov_Sh.S@bk.ru
Өзбекстан, 83 M. Ulugbek St., Tashkent, 100125
R. Makhmudov
A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
Email: Khushmatov_Sh.S@bk.ru
Өзбекстан, 83 M. Ulugbek St., Tashkent, 100125
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