Email this article New 3-(4-Propoxybenzyl)-5-Sulfanyl-Substituted (4H)-1,2,4-Triazoles and Their Antitumor Activity
- Authors: Ovsepyan T.R.1, Dilanyan S.V.1, Arsenyan F.G.1, Muradyan R.E.1, Minasyan N.S.2, Melik-Ohanjanyan R.G.1
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Affiliations:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Issue: Vol 52, No 5 (2018)
- Pages: 404-407
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245213
- DOI: https://doi.org/10.1007/s11094-018-1830-5
- ID: 245213
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Abstract
3,4-Substituted-(4H)-1,2,4-triazole-5-thiols were synthesized and used for S-alkylation, cyanoethylation, and aminomethylation to produce a series of new 1,2,4-triazole derivatives of interest as biologically active compounds. The antitumor properties of several of the 1,2,4-triazole derivatives were studied.
About the authors
T. R. Ovsepyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Author for correspondence.
Email: tag.hovsepyan@mail.ru
Armenia, 26 Azatutyan Prosp, Erevan, 0014
S. V. Dilanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Armenia, 26 Azatutyan Prosp, Erevan, 0014
F. G. Arsenyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Armenia, 26 Azatutyan Prosp, Erevan, 0014
R. E. Muradyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Armenia, 26 Azatutyan Prosp, Erevan, 0014
N. S. Minasyan
Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Armenia, Erevan, 0014
R. G. Melik-Ohanjanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Armenia, 26 Azatutyan Prosp, Erevan, 0014
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