New 3-(4-Propoxybenzyl)-5-Sulfanyl-Substituted (4H)-1,2,4-Triazoles and Their Antitumor Activity
- Авторы: Ovsepyan T.1, Dilanyan S.1, Arsenyan F.1, Muradyan R.1, Minasyan N.2, Melik-Ohanjanyan R.1
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Учреждения:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Выпуск: Том 52, № 5 (2018)
- Страницы: 404-407
- Раздел: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245213
- DOI: https://doi.org/10.1007/s11094-018-1830-5
- ID: 245213
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Аннотация
3,4-Substituted-(4H)-1,2,4-triazole-5-thiols were synthesized and used for S-alkylation, cyanoethylation, and aminomethylation to produce a series of new 1,2,4-triazole derivatives of interest as biologically active compounds. The antitumor properties of several of the 1,2,4-triazole derivatives were studied.
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Об авторах
T. Ovsepyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Автор, ответственный за переписку.
Email: tag.hovsepyan@mail.ru
Армения, 26 Azatutyan Prosp, Erevan, 0014
S. Dilanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Армения, 26 Azatutyan Prosp, Erevan, 0014
F. Arsenyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Армения, 26 Azatutyan Prosp, Erevan, 0014
R. Muradyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Армения, 26 Azatutyan Prosp, Erevan, 0014
N. Minasyan
Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Армения, Erevan, 0014
R. Melik-Ohanjanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: tag.hovsepyan@mail.ru
Армения, 26 Azatutyan Prosp, Erevan, 0014