Enviar artigo por via de e-mail Quantitative HPLC Determination of γ-Aminobutyric Acid Derivative Mefebut in Bioassays
- Autores: Smirnova L.1,2, Ryabukha A.1,2, Suchkov E.1,2, Kuznetsov K.1,2, Tyurenkov I.1, Bakulin D.1
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Afiliações:
- Volgograd State Medical University
- Volgograd Medical Research Center
- Edição: Volume 53, Nº 3 (2019)
- Páginas: 272-274
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245725
- DOI: https://doi.org/10.1007/s11094-019-01991-4
- ID: 245725
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Resumo
A quantitative HPLC method was developed for analyzing mefebut in pharmacokinetic studies. The method was highly sensitive and selective and could be used for determinations in bioassays. The optimized sample-preparation method did not significantly influence the standard error of the quantitative determination.
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Sobre autores
L. Smirnova
Volgograd State Medical University; Volgograd Medical Research Center
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131; 1 Pavshchikh Bortsov Sq., Volgograd, 400131
A. Ryabukha
Volgograd State Medical University; Volgograd Medical Research Center
Autor responsável pela correspondência
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131; 1 Pavshchikh Bortsov Sq., Volgograd, 400131
E. Suchkov
Volgograd State Medical University; Volgograd Medical Research Center
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131; 1 Pavshchikh Bortsov Sq., Volgograd, 400131
K. Kuznetsov
Volgograd State Medical University; Volgograd Medical Research Center
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131; 1 Pavshchikh Bortsov Sq., Volgograd, 400131
I. Tyurenkov
Volgograd State Medical University
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131
D. Bakulin
Volgograd State Medical University
Email: annriabuha@gmail.com
Rússia, 1 Pavshchikh Bortsov Sq., Volgograd, 400131
