An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity


Дәйексөз келтіру

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Аннотация

A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.

Авторлар туралы

M. Plotnikov

E. D. Goldberg Science Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Medical Research Center

Хат алмасуға жауапты Автор.
Email: mbp2001@mail.ru
Ресей, 3 Lenin Prospekt, Tomsk, 634028

L. Zibareva

Tomsk National State Research University

Email: mbp2001@mail.ru
Ресей, 36 Lenin Prospekt, Tomsk, 634050

A. Vasil’ev

E. D. Goldberg Science Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Medical Research Center

Email: mbp2001@mail.ru
Ресей, 3 Lenin Prospekt, Tomsk, 634028

O. Aliev

E. D. Goldberg Science Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Medical Research Center

Email: mbp2001@mail.ru
Ресей, 3 Lenin Prospekt, Tomsk, 634028


© Springer Science+Business Media, LLC, part of Springer Nature, 2017

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