Мақаланы E-mail арқылы жіберу Rapid HPLC-MS/MS Determination of Carbamazepine and Carbamazepine-10,11-Epoxide
- Авторлар: Rodina T.1,2, Mel’nikov E.3,2, Sokolov A.1,3, Prokof’ev A.1,3,2, Arkhipov V.1,3,2, Aksenov A.3, Pozdnyakov D.2
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Мекемелер:
- Federal Scientific Centre for Expert Evaluation of Medical Products, Ministry of Public Health of the Russian Federation
- I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
- I. M. Sechenov First Moscow State Medical University
- Шығарылым: Том 50, № 6 (2016)
- Беттер: 419-423
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244408
- DOI: https://doi.org/10.1007/s11094-016-1462-6
- ID: 244408
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
A rapid HPLC-MS/MS method for simultaneous determination of carbamazepine and carbamazepine- 10,11-epoxide in human blood serum was developed. The analytical range for carbamazepine was 50 – 20,000 ng/mL; for carbamazepine-10,11-epoxide, 5 – 2,000 ng/mL. This allowed the developed method to be used for therapeutic drug monitoring, bioequivalence studies, and an assessment of the interchangeability of carbamazepine preparations.
Авторлар туралы
T. Rodina
Federal Scientific Centre for Expert Evaluation of Medical Products, Ministry of Public Health of the Russian Federation; I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
Email: chem@folium.ru
Ресей, Moscow, 127051; Moscow, 109240
E. Mel’nikov
I. M. Sechenov First Moscow State Medical University; I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
Email: chem@folium.ru
Ресей, Moscow, 119991; Moscow, 109240
A. Sokolov
Federal Scientific Centre for Expert Evaluation of Medical Products, Ministry of Public Health of the Russian Federation; I. M. Sechenov First Moscow State Medical University
Email: chem@folium.ru
Ресей, Moscow, 127051; Moscow, 119991
A. Prokof’ev
Federal Scientific Centre for Expert Evaluation of Medical Products, Ministry of Public Health of the Russian Federation; I. M. Sechenov First Moscow State Medical University; I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
Email: chem@folium.ru
Ресей, Moscow, 127051; Moscow, 119991; Moscow, 109240
V. Arkhipov
Federal Scientific Centre for Expert Evaluation of Medical Products, Ministry of Public Health of the Russian Federation; I. M. Sechenov First Moscow State Medical University; I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
Email: chem@folium.ru
Ресей, Moscow, 127051; Moscow, 119991; Moscow, 109240
A. Aksenov
I. M. Sechenov First Moscow State Medical University
Email: chem@folium.ru
Ресей, Moscow, 119991
D. Pozdnyakov
I. V. Davydovsky Municipal Clinical Hospital, Moscow City Department of Health
Email: chem@folium.ru
Ресей, Moscow, 109240
