Enviar artigo por via de e-mail Synthesis of silicon dioxide xerogels and their sorption- desorption properties with respect to nicotine and glycols
- Autores: Grigoryan S.1, Hakopyan E.1, Hakobyan R.1, Farmazyan Z.1, Atabekyan M.1, Topuzyan V.1
-
Afiliações:
- Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
- Edição: Volume 93, Nº 8 (2023)
- Páginas: 1281-1291
- Seção: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/141624
- DOI: https://doi.org/10.31857/S0044460X23080139
- EDN: https://elibrary.ru/IYYBAQ
- ID: 141624
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
Composites based on silicon dioxide xerogels containing glycerol and nicotine were prepared by hydrolysis of tetraethoxysilane by a single-stage synthesis and two-stage sorption method with a single-stage glycerol sorption in relation to the sorbent reaches 3: 1 by weight. The kinetics of release (desorption) of nicotine from an aerosol mixture with glycols has been studied. The synthesized sorbent is promising for use in aerosol generating systems, as well as carriers and delivery systems for biologically active substances and medicines.
Palavras-chave
Sobre autores
S. Grigoryan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
Email: grigstepan@yahoo.com
E. Hakopyan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
R. Hakobyan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
Z. Farmazyan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
M. Atabekyan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
V. Topuzyan
Scientific and Technological Centre of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia, A.L. Mnjoyan Institute of Fine Organic Chemistry
Bibliografia
- Hoffmann F., Cornelius M., Morell J., Froba M. // Angew. Chem. Int. Ed. 2006. Vol. 45. N 20. P. 3216. doi: 10.1002/anie.200503075
- Simovic S., Ghouchi-Eskandar N., Moom Sinn A., Losic D., Prestidge D. // Curr. Drug Discov. Technol. 2011. N 8. P. 250. doi: 10.2174/157016311796799026
- Mamaeva V., Sahlgren C., Lindén M. // Adv. Drug Deliv. Rev. 2013. Vol. 65. N 5. P. 689. doi: 10.1016/j.addr.2012.07.018
- Şen Karaman D., Kettiger H. In: Inorganic Frameworks as Smart Nanomedicines / Ed. A.M. Grumezescu. Elsevier, 2018. P. 1.
- Li T., Geng T., Md A., Banerjee P., Wang B. // Colloids Surfaces (B). 2019. Vol. 176. P. 185. doi: 10.1016/j.colsurfb.2019.01.004
- Hua Q., Lu W., Zheng S., Zhang Y., Zhang W., Wu D., Shen Y. // Thermochim. Acta. 2017. Vol. 656. P. 53. doi: 10.1016/j.tca.2017.08.013
- Qian K.K., Bogner R.H. // J. Pharm. Sci. 2012. Vol. 101. N 2. P. 444. doi: 10.1002/jps.22779
- Narayan R., Nayak U., Raichur A., Garg S. // Pharmaceutics. 2018. Vol. 10. N 3. P. 118. doi: 10.3390/pharmaceutics10030118
- Stöber W., Fink A., Bohn E. // J. Colloid Interface Sci. 1968. Vol. 26. N 1. P. 62. doi: 10.1016/0021-9797(68)90272-5
- Beck J.S., Vartuli J.C., Roth W.J., Leonowicz M.E., Kresge C.T., Schmitt K.D., Schlenker J.L. // J. Am. Chem. Soc. 1992. Vol. 114. N 27. P. 10834. doi: 10.1021/ja00053a020
- Zhao D. // Science. 1998. Vol. 279. N 5350. P. 548. doi: 10.1126/science.279.5350.548
- Пат. РФ 2382046 С1; Б. И. 2010. № 5.
- Пат. РФ 2255939 С2; Б. И. 2005. № 19.
- Khonina T.G., Safronov A.P., Ivanenko M.V., Shadrina E.V., Chupakhin O.N. // J. Mat. Chem. (B). 2015. N 3. P. 5490. doi: 10.1039/c5tb00480b
- Klein L.C., Garvey G.J. // Mat. Res. Soc. Symp. Proc. 1984. Vol. 32. P. 33.
- Donatti D.A., Dimas R.V. // J. Sol-Gel Sci. Technol. 2000. Vol. 17. P. 19.
