Synthesis of new fused 3(4)-substituted 11-furylthieno[3,2-d]pyrimidine derivatives
- 作者: Dabaeva V.1, Baghdasaryan M.1, Barkhudaryants I.1, Paronikyan E.1, Dashyan S.1
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隶属关系:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
- 期: 卷 93, 编号 9 (2023)
- 页面: 1351-1357
- 栏目: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/141632
- DOI: https://doi.org/10.31857/S0044460X23090056
- EDN: https://elibrary.ru/WWEFRF
- ID: 141632
如何引用文章
详细
A method was developed for the synthesis of new fused 3-alkyl-substituted derivatives of thieno[3,2- d ]pyrimidin-4(3 H )-ones based on 11-(2-furyl)-8,8-dimethyl-7,10-dihydro-8 H -pyrano[3′′,4′′:5′,6′]pyrido[3′,2′:4,5]-thieno[3,2- d ]pyrimidin-4(3 H )-one via nucleophilic substitution in the pyrimidine ring. A series of fused 4-amino-substituted 11-furylthieno[3,2- d ]pyrimidine derivatives was also synthesized from the corresponding 4-chloro derivative.
作者简介
V. Dabaeva
Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
Email: valyadabayeva@mail.ru
M. Baghdasaryan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
I. Barkhudaryants
Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
E. Paronikyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
Sh. Dashyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Science of the Republic of Armenia
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