Synthesis, luminescent properties and antibacterial activity of new pyrazoline and pyrimidine derivatives of (2 e )-1-biphenyl-3-arylprop-2-en-1-ones

A. U. Isakhanyan; Исаханян А. У.; N. Z. Hakobyan; Акопян Н. З.; Z. A. Hovasyan; Овасян З. А.; G. S. Grigoryan; Григорян Г. С.; R. P. Mkhitaryan; Мхитарян Р. П.; H. G. Aracelyan; Аракелян А. Г.; A. S. Safaryan; Сафарян А. С.; R. E. Muradyan; Мурадян Р. Е.; H. A. Panosyan; Паносян Г. А.

doi:10.31857/S0044460X23090032

Synthesis, luminescent properties and antibacterial activity of new pyrazoline and pyrimidine derivatives of (2e)-1-biphenyl-3-arylprop-2-en-1-ones

作者: Isakhanyan A.U.¹, Hakobyan N.Z.¹, Hovasyan Z.A.¹, Grigoryan G.S.², Mkhitaryan R.P.¹, Aracelyan H.G.¹, Safaryan A.S.¹, Muradyan R.E.¹, Panosyan H.A.¹
隶属关系:
1. Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia
2. Yerevan State University
期: 卷 93, 编号 9 (2023)
页面: 1335-1342
栏目: Articles
URL: https://journals.rcsi.science/0044-460X/article/view/141630
DOI: https://doi.org/10.31857/S0044460X23090032
EDN: https://elibrary.ru/WWNIDR
ID: 141630

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Substituted prop-2-en-1-ones were obtained by the condensation reaction of 1-biphenyl-4-yl-ethanone with aromatic aldehydes in the presence of sodium hydroxide in an aqueous ethanol solution. Subsequent cyclization of the latter with hydrazine hydrate, phenylhydrazine, and thiosemicarbazide in an acidic medium leads to the corresponding pyrazolines. The reaction of amidine hydrochlorides with chalcones in a KOH-ethanol system leads to 2,4,6-trisubstituted pyrimidines. The luminescent and antibacterial properties of the resulting systems was studied.

关键词

substituted prop-2-en-1-ones, luminescence, pyrazolines, pyrimidines, cyclization, antibacterial activity

参考

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卷 95, 编号 1-2 (2025)

Synthesis, luminescent properties and antibacterial activity of new pyrazoline and pyrimidine derivatives of (2e)-1-biphenyl-3-arylprop-2-en-1-ones

全文:

详细

关键词

作者简介

A. Isakhanyan

N. Hakobyan

Z. Hovasyan

G. Grigoryan

R. Mkhitaryan

H. Aracelyan

A. Safaryan

R. Muradyan

H. Panosyan

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