Relationships of Enantioselective Retention of Chiral Oxazolopyrroloquinolones on a Stationary Phase with Grafted Ristocetin А Antibiotic from Aqueous Methanol Solutions

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

The mechanisms of retention and separation of the enantiomers of chiral oxazolopyrroloquinolones on a stationary phase with graftеd macrocyclic antibiotic ristocetin A under conditions of high-performance liquid chromatography with aqueous methanol mobile phases have been studied. The retention factor was found to decrease monotonically when the CH3OH concentration in the mobile phase increased to 90 vol %; then it slightly increased as the composition of the mobile phase approached pure methanol. The thermodynamics of adsorption of oxazolopyrroloquinolones in different regions of this dependence was studied. A mathematical model has been proposed; it describes well the experimental data and allows for analyte solvation in the mobile phase and competitive adsorption (with mobile phase components) on a chiral selector. The results were compared with previously obtained data for water–acetonitrile mobile phases. The reasons for the observed differences were discussed.

Авторлар туралы

M. Stepanova

Perm National Research Polytechnical University

Email: asninld@mail.ru
614990, Perm, Russia

L. Asnin

Perm National Research Polytechnical University

Email: asninld@mail.ru
614990, Perm, Russia

A. Boteva

Perm National Research Polytechnical University

Хат алмасуға жауапты Автор.
Email: asninld@mail.ru
614990, Perm, Russia

Әдебиет тізімі

  1. Шаповалова Е.Н., Федорова И.А., Ананьева И.А., Шпигун О.А. // Журн. аналит. химии. 2018. Т. 73. С. 843. https://doi.org/10.1134/S1061934818110114
  2. Cardoso P.A., Cesar I.C. // Chromatographia. 2018. V. 81. P. 841. https://doi.org/10.1007/s10337-018-3526-0
  3. Armstrong D.W., Tang Y., Zhou Y. et al. // Anal. Chem. 1994. V. 66. P. 1473. https://doi.org/10.1021/ac00081a019
  4. Armstrong D.W., Liu Y., Ekborgott K.H. // Chirality. 1995. V. 7. P. 474. https://doi.org/10.1002/chir.530070614
  5. Jandera P., Škavrada M., Klemmová K. et al. // J. Chromatogr. A. 2001. V. 917. P. 123. https://doi.org/10.1016/S0021-9673(01)00701-4
  6. Кузнецов М.А., Нестеренко П.Н., Васияров Г.Г., Староверов С.М. // Журн. аналит. химии. 2008. Т. 63. № 1. С. 64. https://doi.org/10.1007/s10809-008-1011-x
  7. Orosz T., Grecso N., Lajkó G. et al. // J. Pharm. Biomed. Anal. 2017. V. 145. P. 119. https://doi.org/10.1016/j.jpba.2017.06.010
  8. Asnin L.D., Kopchenova M.V., Vozisov S.E. et al. // J. Chromatogr. A. 2020. V. 1626. Art. 461371. https://doi.org/10.1016/j.chroma.2020.461371
  9. Решетова Е.Н., Аснин Л.Д. // Журн. физ. химии. 2011. Т. 85. № 8. С. 1552. https://doi.org/10.1134/S0036024411080280
  10. Gogolishvili O.S., Reshetova E.N. // Chromatographia. 2021. V. 84. P. 53. https://doi.org/10.1007/s10337-020-03978-w
  11. Степанова М.В., Аснин Л.Д., Ботева А.А. и др. // Журн. физ. химии. 2021. Т. 95. № 1. С. 131. https://doi.org/10.1134/S0036024421010271
  12. Snyder L.R., Dolan J.W., Gant J.R. // J. Chromatogr. 1979. V. 165. P. 3. https://doi.org/10.1016/S0021-9673(00)85726-X
  13. Snyder L.R., Poppe H. // Chromatogr. 1980. V. 184. P. 363. https://doi.org/10.1016/S0021-9673(00)93872-X
  14. Soczewinski E. // Anal. Chem. 1969. V. 41. P. 179; https://doi.org/10.1021/ac60270a035
  15. Tsui H.W., Kuo C.H., Huang Y.C. // J. Chromatogr. A, 2019. V. 1595. P. 127. https://doi.org/10.1016/j.chroma.2019.02.049
  16. Ботева А.А., Красных О.П., Солодников С.Ю. Пат. РФ № 2381229 // Б.И. 2010. № 4.
  17. Asnin L.D., Stepanova M.V. // J. Sep. Sci. 2018. V. 41. P. 1219. https://doi.org/10.1002/jssc.201701264
  18. Ekborg-Ott K.H., Liu Y., Armstrong D.W. // Chirality. 1998. V. 10. P. 434. https://doi.org/10.1002/(SICI)1520-636X(1998)10:5<434::AID-CHIR10>3.0.CO;2-0
  19. Климова Я.А., Аснин Л.Д. // Журн. физ. химии. 2021. Т. 95. № 11. С. 1739. https://doi.org/10.1134/S0036024421110091

© М.В. Степанова, Л.Д. Аснин, А.А. Ботева, 2023

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