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DETECTION OF METRONIDAZOLE AND FAMPRIDINE BY NMR AT ZERO AND ULTRALOW MAGNETIC FIELD
- Authors: Burueva D.B1, Eills J.2,3,4, Picazo-Frutos R.2,3,4, Kovtunov K.V1, Budker D.2,3,4,5, Koptyug I.V1
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Affiliations:
- International Tomography Center Siberian Branch of Russian Academy of Sciences
- Helmholtz-Institut Mainz
- GSI Helmholtzzentrum für Schwerionenforschung GmbH
- Institute of Physics, Johannes Gutenberg-Universität
- Department of Physics, University of California
- Issue: Vol 166, No 4 (2024)
- Pages: 566-570
- Section: Articles
- URL: https://journals.rcsi.science/0044-4510/article/view/268183
- DOI: https://doi.org/10.31857/S0044451024100134
- ID: 268183
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Abstract
In this work the biocompatible molecules — metronidazole and fampridine — were successfully hyperpolarized using parahydrogen via the signal amplification by reversible exchange approach. The nuclear magnetic resonance (NMR) signals from both molecules were detected at zero- to ultralow magnetic field (ZULF) using commercially available rubidium vapor magnetometer from QuSpin.
About the authors
D. B Burueva
International Tomography Center Siberian Branch of Russian Academy of Sciences
Author for correspondence.
Email: burueva@tomo.nsc.ru
Russian Federation, 630090, Novosibirsk
J. Eills
Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität
Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany
R. Picazo-Frutos
Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität
Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany
K. V Kovtunov
International Tomography Center Siberian Branch of Russian Academy of Sciences
Email: burueva@tomo.nsc.ru
Russian Federation, Novosibirsk
D. Budker
Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität; Department of Physics, University of California
Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany; Berkeley, USA
I. V Koptyug
International Tomography Center Siberian Branch of Russian Academy of Sciences
Email: koptyug@tomo.nsc.ru
Russian Federation, Novosibirsk
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