Erythema nodosum as Leprosy reaction
- 作者: Semenova V.G.1, Makarova L.L.1, Karamova A.E.1
-
隶属关系:
- State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
- 期: 卷 96, 编号 3 (2020)
- 页面: 68-74
- 栏目: CLINICAL CASE REPORTS
- URL: https://journals.rcsi.science/0042-4609/article/view/117536
- DOI: https://doi.org/10.25208/vdv1159
- ID: 117536
如何引用文章
全文:
详细
Purpose. To present a clinical case of leprosy exacerbation on the background of ongoing therapy.
Materials and methods. A 52-year-old patient with a diagnosis of "lepromatous (cutaneous) leprosy, leprosy LL" (multi-bacterial leprosy, lepromatous form, active stage), has an exacerbation in the form of nodular erythema at 3.5 years after the start of treatment. Due to the exacerbation of the leprosy process, dexamethasone therapy was performed intravenously in a dose of 4 mg/ml — 3.0 ml + 0.9% NaCl 200.0 ml daily No. 10.
Results. An exacerbation was diagnosed — leprosy nodular erythema. The prescription of adequate therapy led to a complete regression of clinical manifestations.
Conclusion. The described case is presented in connection with the rarity of this dermatosis.
作者简介
Viktoria Semenova
State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: v.g.semenova@mail.ru
Director, Sergiev Posad Branch of the State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
俄罗斯联邦, Korolenko str., 3, bldg 6, MoscowLudmila Makarova
State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
Email: semenova@mail.ru
Head of the leprosy Department, Sergiev Posad Branch of the State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
俄罗斯联邦, Korolenko str., 3, bldg 6, MoscowArfenya Karamova
State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
Email: semenova@mail.ru
Cand. Sci. (Med.), Head of the Dermatology Department, State Research Center of Dermatovenereology and Cosmetology, Ministry of Health of the Russian Federation
俄罗斯联邦, Korolenko str., 3, bldg 6, Moscow参考
- Boggild A.K., Keystone J.S., Kain K.C. Leprosy: a primer for Canadian physicians. CMAJ, 2004; 170 (1): 71—8.
- Семенова В.Г., Карамова А.Э., Нефедова М.А., Чеботарев В.В., Земцов М.А., Одинец А.В., Шиханова Е.Н., Чумакова Е.С. Случай погранично-туберкулоидной лепры с атипичными и осложненными проявлениями. Вестник дерматологии и венерологии. 2019; 95 (4): 67—78. [Semenova V.G., Karamova A.E., Nefyodova M.A., Chebotarev V.V., Zemtsov M.A., Odinets A.V., Shikhanova E.N., Chumakova E.S. A case of borderline tuberculoid leprosy with atypical and complicated manifestations. Vestnik Dermatologii i Venerologii. 2019; 95 (4): 67—78. https://doi.org/10.25208/0042-4609-2019-95-4-67-78 (Russia).]
- Antunes D.E., Goulart I.M.B., Lima M.I.S., Alves P.T., Tavares P.C.B., Goulart L.R. Differential Expression of IFN-, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum. J Immunol Res. 2019; 3405103. Published online 2019, Nov 7.
- Cuevas J., Rodríguez-Peralto J.L., Carrillo R., Contreras F. Erythema nodosum leprosum: reactional leprosy. Semin Cutan Med Surg. 2007; 26 (2): 126—30.
- Costa P.D.S.S., Fraga L.R., Kowalski T.W., Daxbacher E.L.R., Schuler-Faccini L., Vianna F.S.L. Erythema Nodosum Leprosum: Update and challenges on the treatment of a neglected condition. Acta Trop. 2018; 183: 134—141.
- Negera E., Tilahun M., Bobosha K. et al. The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions. PLoS Negl. Trop. Dis. 2018; 12 (12): e0007035.
- Inamadar A.C., Adya K.A. The rash with painful and erythematous nodules. Clin Dermatol. 2019; 37 (2): 129—135.
- Zhu J., Yang D., Shi C., Jing Z. Therapeutic Dilemma of Refractory Erythema Nodosum Leprosum. Am J Trop Med Hyg. 2017; 96 (6): 1362—1364.
补充文件
