Rossolimo–Melkersson–Rosenthal syndrome as a manifestation of lip sarcoidosis
- Authors: Perlamutrov Y.N.1, Drobyshev A.U.1, Olkhovskaya K.B.1, Miterev A.A.1, Plehanova E.N.1
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Affiliations:
- A.I. Yevdokimov Moscow State University of Medicine and Dentistry
- Issue: Vol 98, No 4 (2022)
- Pages: 58-66
- Section: GUIDELINES FOR PRACTITIONERS
- URL: https://journals.rcsi.science/0042-4609/article/view/117630
- DOI: https://doi.org/10.25208/vdv1278
- ID: 117630
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Abstract
A 38-year-old female patient complained of lip augmentation. With a preliminary diagnosis of Rossolimo–Melkersson–Rosenthal syndrome (monosymptomatic form), chronic fissure of the lower lip, the patient was sent for examination in order to exclude tumor pathology and vascular malformation. According to the results of a comprehensive clinical and laboratory examination, it was found that lip enlargement is due to the formation of granulomas. Additional follow-up by a pulmonologist confirmed the presence of sarcoidosis of the lungs with involvement of the mediastinal lymph nodes. A comprehensive examination made it possible to verify the diagnosis of multisystem sarcoidosis in a patient with macrocheilitis. As a result of complex therapy using surgical methods and systemic glucocorticosteroids, a rapid dynamics of clinical symptoms was observed and remission was achieved. This clinical case demonstrates a combination of sarcoid lesions of the tissues of the mediastinal lymph nodes, lung parenchyma and lips. It was the presence of macrocheilitis that was the main reason for visiting a dermatovenereologist and was the reason for choosing the subsequent tactics of examination and treatment. As a result of complex therapy using surgical methods of treatment and systemic glucocorticosteroids, carried out entirely within the framework of the program of state guarantees of free medical care for citizens, a stable remission of the disease was achieved.
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##article.viewOnOriginalSite##About the authors
Yuri N. Perlamutrov
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: y.perlamutrov@mail.ru
ORCID iD: 0000-0002-4837-8489
SPIN-code: 2330-2758
MD, Dr. Sci. (Med), Professor
Russian Federation, 20, bldg 1, Delegatskaya str., Moscow, 127473Alexey U. Drobyshev
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: dr.drobyshev@gmail.com
ORCID iD: 0000-0002-1710-6923
SPIN-code: 6683-8226
MD, Dr. Sci. (Med), Professor
Russian Federation, 20, bldg 1, Delegatskaya str., Moscow, 127473Kira B. Olkhovskaya
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Author for correspondence.
Email: olhovskaya_kira@mail.ru
ORCID iD: 0000-0003-4920-5288
SPIN-code: 9455-9482
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 20, bldg 1, Delegatskaya str., Moscow, 127473Andrey A. Miterev
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: dr.miterev@mail.ru
ORCID iD: 0000-0003-3735-7022
SPIN-code: 3308-1606
MD, Cand. Sci. (Med)
Russian Federation, 20, bldg 1, Delegatskaya str., Moscow, 127473Elena N. Plehanova
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: etsmokalyk@mail.ru
ORCID iD: 0000-0002-8667-9960
Russian Federation, 20, bldg 1, Delegatskaya str., Moscow, 127473
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