Scars: questions of prevention and treatment

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Abstract

Each year in the developed countries of the world 100 million patients acquire scars; and there are 11 million keloid scars among them.

Aim of the study. Evaluate the effectiveness of treatment and dynamics of scar condition when using self-adhesive dressings (silicone sheet; silicone patch) with a layer of soft silicone.

Patients and methods. A clinical prospective observational study of the dynamics of scarring conditions using selfadhesive dressings with a layer of silicone sheet (soft silicone) was conducted in 27 patients.

Results. It was shown that by the third visit (42 days after inclusion in the study); the color changed towards lightening and disappearing red; in the largest group with dark red scars at the beginning of the study 43.7% completed the study with light pink scars; 43.7% with hyperpigmented and 5.26% with normopigmented (р < 0.0001). Also significant was the dynamics of changes in the position of the scar relative to the level of normal skin (р < 0.0001) with level alignment in case it was initially lower than the level of normal skin. The condition of the scar surface by the third visit normalized; in all patients the surface became even (p = 0.0044). There was a marked increase in the number of easily displaceable scars (from 11.1% to 37.0%; p = 0.0003). Also; by the third visit; itching disappeared in all patients (р < 0.0001).

Conclusion. Overall; the study showed marked improvement across all parameters studied. Silicone sheet; one of the most widely used forms of silicone-based dressings; to be an effective treatment scar management.

About the authors

Denis V. Zaslavsky

Saint Petersburg State Pediatric Medical University

Author for correspondence.
Email: venerology@gmail.com
ORCID iD: 0000-0001-5936-6232
SPIN-code: 5832-9510
Scopus Author ID: 0000-0001-5936-6232
ResearcherId: T-2356-2019

MD; Dr. Sci. (Med.); Professor

Russian Federation, Litovskaya str., 2A, 194100, Saint Petersburg

Anna N. Barinova

North-Western State Medical University named after I.I. Mechnikov

Email: Anna.Barinova@szgmu.ru
ORCID iD: 0000-0001-8215-086X
SPIN-code: 2010-4354

MD; Dr. Sci. (Med.); Professor

Russian Federation, Piskarevskij prospect, 47, 195067, Saint Petersburg

Akmal A. Sidikov

Tashkent State Dental Institute

Email: medik-85@bk.ru
ORCID iD: 0000-0002-0909-7588
SPIN-code: 3812-8400

MD; Dr. Sci. (Med.)

Uzbekistan, Makhtumkuli str., 103, 100047, Tashkent

Boris M. Tayts

North-Western State Medical University named after I.I. Mechnikov

Email: boris.tayts@szgmu.ru
SPIN-code: 1579-4967

MD; Dr. Sci. (Med.); Professor

Russian Federation, Piskarevskij prospect, 47, 195067, Saint Petersburg

Svyatoslav L. Plavinskij

North-Western State Medical University named after I.I. Mechnikov

Email: splavinskij@szgmu.ru
ORCID iD: 0000-0001-9159-6177
SPIN-code: 5660-4661

MD; Dr. Sci. (Med.); Professor

Russian Federation, Piskarevskij prospect, 47, 195067, Saint Petersburg

Darya V. Kozlova

Saint Petersburg State Pediatric Medical University

Email: dashauchenaya@yandex.ru
ORCID iD: 0000-0002-6942-2880
SPIN-code: 3783-8565

5th year student

Russian Federation, Litovskaya str., 2A, 194100, Saint Petersburg

Oksana V. Bulina

Saint Petersburg State Pediatric Medical University

Email: oksanabulina@yandex.ru
ORCID iD: 0000-0002-2997-7777
SPIN-code: 7960-2040

MD; Cand. Sci. (Med.); assistant professor

Russian Federation, Litovskaya str., 2A, 194100, Saint Petersburg

References

  1. Bayat A; McGrouther DA; Ferguson MW. Skin scarring. BMJ. 2003;11;326(7380):88–92. doi: 10.1136/bmj.326.7380.88
  2. Sund B. New developments in wound care. PJB Publications: London 1:255 (Clinical Report CBS 836); 2000. doi: 10.1136/bmj.326.7380.88
  3. Горланов И. А.; Леина Л. М.; Милявская И. Р.; Заславский Д. В. Болезни кожи новорожденных и грудных детей. СПб.: Фолиант; 2016. [Gorlanov I A; Leina L M; Milyavskaya I R; Zaslavsky D V. Diseases of the skin of newborns and infants. Saint Petersburg: Foliant Publishing House; 2016 (In Russ.)]
  4. Bell I; McAdamas T; Morgan R; et al. Pruritus in burn: A descriptive study. J Burn Care Rehabil. 1988;9(3):305–308.
  5. Taal I; Faber AW. Posttraumatic stress and maladjustment among adult burn survivors 1 to 2 years postburn: Part II. The interview data. Burns. 1998;24:399. doi: 10;1016/s0305-4179(98)00053-9
  6. Robert R; Meyer W; Bishop S; et al. Disfiguring burn scars and adolescent self-esteem. Burns. 1999;25:581.
  7. doi: 10.1016/s0305-4179(99)00065-0
  8. Dorfmuller M. Psychological management; after care of severely burned patients. Unfallchirurg. 1995;98:213.
  9. doi.org/10.1136/bmj.326.7380.92
  10. Woo SH; Seul JH. Optimizing the correction of severe postburn hand deformities by using aggressive contracture releases and fasciocutaneous free-tissue transfer. Plast Reconstr Surg. 2001;107:1.
  11. doi: 10.1097/00006534-200101000-00001
  12. Mustoe TA; Cooter RD; Gold MH; et al. International clinical recommendations on scar management. Plast Reconstr Surg. 2002;110:560. doi: 10.1097/00006534-200208000-00031.
  13. Родионов А. Н.; Заславский Д. В.; Сыдиков А. А. Дерматология. Иллюстрированное руководство клинической диагностики по профессору Родионову. М.: Граница; 2018. [Rodionov AN; Zaslavsky DV; Sidikov AA. Dermatology. Illustrated clinical diagnostic guide by Professor Rodionov; Moscow: Publishing house Granitsa; 2018 (In Russ.)]
  14. O'Brien L; Jones DJ. Silicone gel sheeting for preventing and treating hypertrophic and keloid scars. Cochrane Database Syst Rev. 2013;2013:9:CD003826. doi: 10.1002/14651858.CD003826.pub3.
  15. Баринова А. Н.; Плавинский С. Л. Оценка эффективности и упрощенная оценка стоимости-эффективности использования современных продуктов; содержащих силикон; в лечении патологических рубцов. Искусство профессионалов красоты. 2015;1:10–12. [Barinova AN; Plavinskij SL. Ocenka effektivnosti i uproshchennaya ocenka stoimosti-effektivnosti ispol'zovaniya sovremennyh produktov; soderzhashchih silikon; v lechenii patologicheskih rubcov. Iskusstvo professionalov krasoty. 2015;(1)10–12 (In Russ.)]
  16. Behrangi E; Goodarzi A; Roohaninasab M; et al. A review of scar treatment related to acne and burn. JCR. 2020;7(04):714–722.
  17. doi: 10.31838/jcr.07.04.133
  18. Glass DA 2nd. Current Understanding of the Genetic Causes of Keloid Formation. J Investig Dermatol Symp Proc. 2017;18(2):50–53.
  19. doi: 10.1016/j.jisp.2016.10.024
  20. El Ayadi A; Jay JW; Prasai A. Current Approaches Targeting the Wound Healing Phases to Attenuate Fibrosis and Scarring. Int J Mol Sci. 2020;7;21(3):1105–1133. doi: 10.3390/ijms21031105
  21. Тайц Б. М. Практическая предиктивная; превентивная и персонализированная медицина. «10П медицина» в решении вопросов профилактики; активного долголетия; снижения смертности и увеличения продолжительности жизни населения. МЗРФ ФГБОУ ВО СЗГМУ им. И. И. Мечникова. СПб.: ИПК Береста; 2019. [Tajc BM. Prakticheskaya prediktivnaya; preventivnaya i personalizirovannaya medicina. “10P medicina” v reshenii voprosov profilaktiki; aktivnogo dolgoletiya; snizheniya smertnosti i uvelicheniya prodolzhitel'nosti zhizni naseleniya. MZRF FGBOU VO SZGMU im. I. I. Mechnikova. Saint Peterburg: IPK Beresta; 2019 (In Russ.)]
  22. Puri N; Talwar A. The efficacy of silicone gel for the treatment of hypertrophic scars and keloids. J Cutan Aesthet Surg. 2009;2(2):104–106. doi: 10.4103/0974-2077.58527
  23. Akaishi S; Akimoto M; Hyakusoku H; Ogawa R. 142B: The relationship between keloid growth pattern and stretching tensionvisual analysis using the finite element method. Plast Reconstr Surg. 2010;125:96. doi: 10.1097/SAP.0b013e3181238dd7
  24. Rabello FB; Souza CD; Farina Júnior JA. Update on hypertrophic scar treatment. Clinics (Sao Paulo). 2014;69:565–573.
  25. doi: 10.6061/clinics/2014(08)11
  26. Borgognoni L. Biological effects of silicone gel sheeting. Wound Repair Regen. 2002;10:118–121. doi: 10.1046/j.1524-475x.2002.00205.x
  27. Bleasdale B; Finnegan S; Murray K. The Use of Silicone Adhesives for Scar Reduction. Adv Wound Care (New Rochelle). 2015;4(7):422–430. doi: 10.1089/wound.2015.0625
  28. Gilman TH. Silicone sheet for treatment and prevention of hypertrophic scar: a new proposal for the mechanism of efficacy. Wound Repair Regen. 2003;11:235–236. doi: 10.1046/j.1524-475x.2003.11313.x

Supplementary files

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1. JATS XML
2. Fig. 1. Jean-Louis Marc Alibert (1768–1837)

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3. Fig. 2. Keloid Scars. Jean-Louis Alibert (1835). Monographie des dermatoses (in French) (2nd ed.)

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4. Fig. 3. Keloid scar after thyroidectomy: a — before treatment; б — after 2 weeks after treatment; в — after 1 month after treatment

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5. Fig. 4. Scar: a — before treatment; б — after 2 weeks after treatment; в — after 1 month after treatment

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6. Fig. 5. Scar: a — before treatment; б — after 2 weeks after treatment; в — after 1 month after treatment

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7. Fig. 6. Scar: a — before treatment; б — after 2 weeks after treatment; в — after 1 month after treatment

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Copyright (c) 2021 Zaslavsky D.V., Barinova A.N., Sidikov A.A., Tayts B.M., Plavinskij S.L., Kozlova D.V., Bulina O.V.

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