Clinical case of Bloch — Sulzberger syndrome
- Authors: Krasnova N.V.1, Chernova T.A.2, Alekseeva I.V.1, Gimalieva G.G.1, Misyakova T.1, Sinitsyna L.G.1
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Affiliations:
- BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
- State Autonomous Institution of the Chuvash Republic of Continuing Professional Education "Institute for Advanced Medical Studies" of the Ministry of Health of the Chuvash Republic
- Issue: Vol 96, No 3 (2020)
- Pages: 63-67
- Section: CLINICAL CASE REPORTS
- URL: https://journals.rcsi.science/0042-4609/article/view/117531
- DOI: https://doi.org/10.25208/vdv1117
- ID: 117531
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Abstract
Purpose. To present a clinical case of Bloch — Sulzberger syndrome.
Material and methods. The examinations were performed to diagnose the disease: а visual examination of the skin, cytological analysis of the gallbladder fluid, general and biochemical blood tests, genetic research.
Results. During a visual examination of the skin, a differential diagnosis was made with infectious dermatitis, toxic-allergic dermatitis, epidermolysis bullosa and linear IgA-dependent dermatosis in children. Crucial in the diagnosis belonged to a genetic study, after which a deletion of exons 4—10 of the IKBKG gene was detected, which confirmed Bloch — Sulzberger syndrome.
Conclusion. Newborns with vesicle-bullous rashes entering the neonatal pathology department and observed by neonatologists require a thorough examination, a mandatory consultation of a dermatologist in order to determine further management tactics.
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##article.viewOnOriginalSite##About the authors
Nadezhda V. Krasnova
BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
Email: Laricasiniczyna@yandex.ru
Chief Physician of the Budgetary Institution "Republican Dermatovenerologic Dispensary" of the Ministry of Health of the Chuvash Republic
Russian Federation, Pirogova str., 6, CheboksaryTatyana A. Chernova
State Autonomous Institution of the Chuvash Republic of Continuing Professional Education "Institute for Advanced Medical Studies" of the Ministry of Health of the Chuvash Republic
Email: Laricasiniczyna@yandex.ru
Candidate of Medical Sciences, Honored Doctor of the Russian Federation, Head of the Dermatovenerology Course at State Autonomous Institution of the Chuvash Republic of Additional Professional Education "Institute for Advanced Medical Education" of the Ministry of Health of the Chuvash Republic
Russian Federation, Mikhail Sespel str., 27, CheboksaryIrina V. Alekseeva
BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
Email: Laricasiniczyna@yandex.ru
Deputy Chief Physician for clinical expert work of the Budgetary Institution "Republican Dermatovenerologic Dispensary" of the Ministry of Health of the Chuvash Republic
Russian Federation, Pirogova str., 6, CheboksaryGeliya G. Gimalieva
BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
Email: Laricasiniczyna@yandex.ru
Head of the Consultative and Diagnostic Department of the Budgetary Institution "Republican Dermatovenerologic Dispensary" of the Ministry of Health of the Chuvash Republic
Russian Federation, Pirogova str., 6, CheboksaryTatiana Misyakova
BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
Email: Laricasiniczyna@yandex.ru
Physician of the Consultative and Diagnostic Department of the Budgetary Institution "Republican Dermatovenerologic Dispensary" of the Ministry of Health of the Chuvash Republic
Russian Federation, Pirogova str., 6, CheboksaryLarisa G. Sinitsyna
BI of the Chuvash Republic “Republican Dermatovenereologic Dispensary” of the Ministry of Health of the Chuvash Republic
Author for correspondence.
Email: Laricasiniczyna@yandex.ru
Physician of the consultative and diagnostic department of the Budgetary Institution "Republican Dermatovenerologic Dispensary" of the Ministry of Health of the Chuvash Republic, the author responsible for correspondence
Russian Federation, Pirogova str., 6, CheboksaryReferences
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