Acne in women with adrenic hyperandrogenism

Goal. Study of clinical and laboratory signs of adrenal hyperandrogenism in women with acne. Маterials and methods. 303 women with acne have been examined at the age of 20—40 years. The anamnesis has been studied and tests have been performed in order to determine the life quality as well as dermatologic and gynecologic examination with pilosis evaluation based on the Ferriman-Gallwey score , anthropometric and general clinical examination, endocrine profile studies, urine steroid profile, biochemical blood composition, as well as pelvic ultrasound and sebumetry. Results. The authors identified a group of women (n = 31) with the early onset of acne, hirsutism, android adiposity, prevalence of non-inflammatory skin eruptions, seborrhea, endocrine profile diseases according to blood test results and determination of the urine steroid profile, metabolic deviations, ineffective treatment with oral contraceptives. Conclusion. The authors revealed specific clinical and laboratory signs that can be referred to diagnostic criteria of adrenal hyperandrogenism in women with acne, which will make it possible to select the rational treatment for this category of patients in future.

acne in women, clinical and laboratory signs, adrenal hyperandrogenism