Treatment of mixed skin infections

Goal. To assess the tolerance, efficacy and cosmetic acceptability of a combined topical product on the basis of a cream for the treatment of dermatoses of mixed etiology localized in skin areas with thin epidermis (intertriginous affections, face affections, cheilites). Materials and methods. This prospective, open-label, cohort study involved 40 male and female patients aged 22-58 with the diagnosed mycosis of large skin folds (n = 28), dermatoses of mixed etiology in skin areas with thin epidermis (face, ears, scrotum) (n = 12). This group comprised patients with impetigo in the beard area (n = 1), mycosis of auricle skin and postaural area (n = 2), atopic eyelid dermatitis complicated with a secondary infection (n = 4), commissural cheilitis (n = 2) and scrotum skin mycosis (n = 3).The patients received treatment on their own for 10-30 days. The treatment efficacy assessment was based on the doctor’s opinion concerning the symptom intensity and patients’ opinion with regard to their symptoms and complaints. Results. The authors revealed evident clinical efficacy and safety of the combination drug (Candiderm) for the treatment of dermatoses with secondary flora in skin folds and delicate skin areas. This study demonstrates that the Candiderm cream is a highly efficient and safe drug, which does not inhibit the adrenal cortex, well-tolerated and convenient in application.

dermatoses of mixed etiology, skin with thin epidermis, beclomethasone dipropionate, gentamicin, clotrimazole