Nikolsky’s sign - a rare form of alopecia areata
- Authors: Mareeva A.N.1, Kondrakhina I.N.1
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Affiliations:
- State Research Center of Dermatovenereology and Cosmetology
- Issue: Vol 91, No 5 (2015)
- Pages: 97-101
- Section: Articles
- URL: https://journals.rcsi.science/0042-4609/article/view/116771
- DOI: https://doi.org/10.25208/0042-4609-2015-91-5-97-101
- ID: 116771
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Abstract
Two case reports of rare form of alopecia areata - Nikolsky’s sign - were presented. This disease is often associated with nerve system pathology (schizophrenia, epilepsy, hysteroid reactions). A special feature of first monitoring was the combination of Nikolsky’s sign as a form of alopecia areata and Down syndrome. Trichodermatoscopy with detection of characteristic stigmas of alopecia areata can provide assistance in differential diagnostics of this disease and other disorders.
About the authors
A. N. Mareeva
State Research Center of Dermatovenereology and Cosmetology
Author for correspondence.
Email: nastasya_66@mail.ru
Russian Federation
I. N. Kondrakhina
State Research Center of Dermatovenereology and Cosmetology
Email: noemail@neicon.ru
Russian Federation
References
- Gilhar A., Paus R., Kalish R.S. Lymphocytes, neuropeptides, and genes involved in alopecia areata. J Clin Invest 2007; Aug 1; 117 (8): 2019-2027.
- Price V. J Invest Dermatol Symp Proc 2003; 8: 207-211.
- Tosti A., Bellavista S., Iorizzo M. Alopecia areata: a long term follow-up study of 191 patients. J Am Acad Dermatol 2006; 55: 438-441.
- Wasserman D., Guzman-Sanchez D.A., Scott K., McMichael A. Alopecia areata. Int J Dermatol 2007; 46; 121-131. Литература
- Суворова К.Н., Варданян К.Л. Эволюция терапии гнездной алопеции и современная дерматологическая практика. Вестн дерматол венерол 2004; (5): 9-15.
- Адаскевич В.П., Мяделец О.Д., Тихоновская И.В. Алопеция. М: Мед. книга, Нижний Новгород: НГМА 2000.
- Schepis C., Barone C., Siragusa M., Pettinato R., Romano C. An updated survey on skin conditions in Down syndrome. Dermatology 2002; 205: 234-238.
- Schepis C., Barone C., Lazzaro Danzuso G.C., Romano C. Alopecia areata in Down syndrome: a clinical evaluation. J Eur Acad Dermatol Venereol 2005 Nov; 19 (6): 769-70.
- Дерматовенерология, 2008 Под ред. А.А.Кубановой. М: ДЭкС-ПРЕСС; 2008.
- Клиническая дерматовенерология: руководство в 2 т (Под ред. Ю.К. Скрипкина, Ю.С. Бутова). М: ГЭОТАР-Медиа, 2009.
- Inui S., Nakajima T., Nakagawa K., Itami S. Clinical significance of dermoscopy in alopecia areata: analysis of 300 cases Int J Dermatol 2008 Jul; 47 (7): 688-93.
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