Application of exifine in etiotropic treatment of zooanthroponotic trichophytia
- Authors: Hismatullina Z.R.1, Danilenko R.U.1, Sultanbaeva A.U.1, Mukhamadeeva O.R.1
-
Affiliations:
- Bashkortostan State Medical University
- Issue: Vol 90, No 6 (2014)
- Pages: 171-176
- Section: DRUG TREATMENT IN DERMATOVENEROLOGY
- URL: https://journals.rcsi.science/0042-4609/article/view/116742
- DOI: https://doi.org/10.25208/0042-4609-2014-90-6-171-176
- ID: 116742
Cite item
Full Text
Abstract
We have studied effect of Exifine on the dynamics of infectious process and some parts of the immune response at different stages of zooanthroponotic trichophytosis development. Functional activity of neutrophils, CD3, CD4, CD8, CD16, CD72, HLA-DR lymphocyte markers, TNFa, IL-1 β, IL-4 and IFN-γ cytokines were determined using immunological studies. Histomorphological changes of affected hair were studied during treatment. Effectiveness of Exifine at zooanthroponotic trichophytosis of scalp and smooth skin in children has been proven: mycological cure and persistent therapeutic effect. Exifine has no immunosuppressive activity as observed in Griseofulvin treatment.
About the authors
Z. R. Hismatullina
Bashkortostan State Medical University
Author for correspondence.
Email: hzr07@mail.ru
Russian Federation
R. U. Danilenko
Bashkortostan State Medical UniversityRussian Federation
A. U. Sultanbaeva
Bashkortostan State Medical UniversityRussian Federation
O. R. Mukhamadeeva
Bashkortostan State Medical UniversityRussian Federation
References
- Сергеев Ю.В., Шпигель Б.И., Сергеев А.Ю. Фармакотерапия микозов. М.: Медицина для всех, 2003. 199 с
- Степанова Ж.В., Гребенюк В.Н., Воробьева И.А., Галустян С.М., Климова И.Я. Диагностические ошибки при зооантропонозной трихофитии. Вестн дерматол и венерол 2001; (6): 36-38
- Хисматуллина З.Р., Медведев Ю.А. Зооантропонозная трихофития. Уфа: ГУП ИПК МВД по РБ «ТиД», 2013. 112 с
Supplementary files
