Extraesophageal signs of gastroesophageal reflux disease: otorhinolaryngologist’s view
- 作者: Radtsig E.1, Konstantinov D.1
-
隶属关系:
- Pirogov Russian National Research Medical University
- 期: 卷 93, 编号 4 (2021)
- 页面: 521-525
- 栏目: Reviews
- URL: https://journals.rcsi.science/0040-3660/article/view/71274
- DOI: https://doi.org/10.26442/00403660.2021.04.200814
- ID: 71274
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详细
The data on association between various pathologies of the ENT organs and gastroesophageal reflux disease (GERD) is analysed in the article. The variety of extraesophageal signs of GERD in children and adults is given, what is advisable to inform physicians of different specialties about the possibilities of antireflux therapy. These options are expanded with the emergence of a unique new drug, Alfasoxx. Its bioadhesive formula is based on hyaluronic acid and chondroitin sulphate thereby protecting the esophageal mucosa. Alfasoxx acts on the surface of the esophageal mucosa without penetrating into the systemic bloodstream and it also has a low allergenic potential, which has been confirmed by numerous studies. With its healing and repairing effect on erosive lesions of the esophageal epithelium, Alfasoxx in combination with proton pump inhibitors is more effective in achieving regression of clinical manifestations of the disease and improving patients’ quality of life (according to SF-36 questionnaire) compared to proton pump inhibitors monotherapy.
作者简介
Elena Radtsig
Pirogov Russian National Research Medical University
编辑信件的主要联系方式.
Email: Radtsig_e@rsmu.ru
ORCID iD: 0000-0003-4613-922X
д.м.н., проф., проф. каф. оториноларингологии педиатрического фак-та
俄罗斯联邦, MoscowDaniil Konstantinov
Pirogov Russian National Research Medical University
Email: Radtsig_e@rsmu.ru
ORCID iD: 0000-0001-7514-4090
клинический ординатор каф. оториноларингологии педиатрического фак-та
俄罗斯联邦, Moscow参考
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