The use of a new semi-quantitative rapid test for procalcitonin in the diagnosis of multisegmental community-acquired pneumonia
- 作者: Bayramova S.1, Nikolayev K.1, Tsygankova O.1,2
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隶属关系:
- Institute of Internal and Preventive Medicine – a branch of The Federal Research Center Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences
- Novosibirsk State Medical University
- 期: 卷 93, 编号 3 (2021)
- 页面: 279-282
- 栏目: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/46397
- DOI: https://doi.org/10.26442/00403660.2021.03.200654
- ID: 46397
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Aim. Evaluation of the possibilities of a new semi-quantitative rapid test for procalcitonin in the diagnosis of multisegmental community-acquired pneumonia.
Materials and methods. A one-stage comparative study involved 123 patients hospitalized in a hospital with a confirmed diagnosis of community-acquired pneumonia. The mean age of the patients was 49.5±21.0 (M±SD) years. On the first day of hospitalization, all patients underwent a general clinical examination, chest x-ray, and a plasma procalcitonin level was determined using a semi-quantitative rapid test.
Results. Indicators of a new semi-quantitative rapid test for procalcitonin of at least 2 ng/ml are directly related to laboratory and instrumental indicators reflecting the severity of community-acquired pneumonia, namely, the severity of respiratory failure (p=0.001), respiratory rate (p=0.001), and heart rate contractions (p=0.001), systolic blood pressure (p=0.025), oxygen saturation (p=0,001), erythrocyte sedimentation rate (p=0.021), fibrinogen (p=0.003) and high CRB-65 scores (p=0.001). They are also associated with multisegmental community-acquired pneumonia (÷2=4.7; p=0.030) and complications of this disease, such as hydrothorax (p=0.029) and death (÷2=22.1; p=0.001).
Conclusion. Using a new semi-quantitative rapid test for procalcitonin allows you to optimize the diagnosis of complications of community-acquired pneumonia and determine the high risk of multisegmental pneumonia.
作者简介
Sabina Bayramova
Institute of Internal and Preventive Medicine – a branch of The Federal Research Center Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: sabina0412@mail.ru
ORCID iD: 0000-0002-4488-2493
мл. науч. сотр. лаб. неотложной терапии НИИТПМ – филиала ИЦиГ СО РАН
俄罗斯联邦, 630089, Russia, Novosibirsk, st. B. Bogatkova, 175/1Konstantin Nikolayev
Institute of Internal and Preventive Medicine – a branch of The Federal Research Center Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences
Email: nikolaevky@yandex.ru
ORCID iD: 0000-0003-4601-6203
д.м.н., проф., зав. лаб. неотложной терапии НИИТПМ – филиала ИЦиГ СО РАН
俄罗斯联邦, 630089, Russia, Novosibirsk, st. B. Bogatkova, 175/1Oksana Tsygankova
Institute of Internal and Preventive Medicine – a branch of The Federal Research Center Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences; Novosibirsk State Medical University
Email: oksana_c.nsk@mail.ru
ORCID iD: 0000-0003-0207-7063
д.м.н., проф. каф. неотложной терапии с эндокринологией и профпатологией ФГБОУ ВО НГМУ, ст. науч. сотр. лаб. клинических биохимических и гормональных исследований терапевтических заболеваний НИИТПМ – филиала ИЦиГ СО РАН
俄罗斯联邦, 630091, Russia, Novosibirsk, st. Krasnyj prospeсt, 52; 630089, Russia, Novosibirsk, st. B. Bogatkova, 175/1参考
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