Anxiety-related blood pressure variability in patients with atrial fibrillation after cardioembolic stroke
- 作者: Zolotovskaya I1, Davydkin I1, Poverennova I1
-
隶属关系:
- ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России
- 期: 卷 89, 编号 12-2 (2017)
- 页面: 150-156
- 栏目: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/32333
- DOI: https://doi.org/10.17116/terarkh20178912150-156
- ID: 32333
如何引用文章
全文:
详细
Aim. To investigate whether of anxiety-related blood pressure (BP) variability can be corrected in patients with atrial fibrillation (AF) who have experienced cardioembolic stroke (CES). Subjects and methods. The investigation enrolled 125 patients (mean age, 68.5±5.7 years) with AF, who had experienced CES. The patients were randomized into 2 groups by the envelope technique: 1) 63 patients received antihypertensive drugs and an anxiolytic (adaptol) (a study group); 2) 62 patients had antihypertensive drugs only (a comparison group). Effectiveness was evaluated 2 and 6 weeks later from the time course of changes in BP readings obtained by 24-hour Holter monitoring in relation to reactive anxiety (RA) and personal anxiety (PA) scores. The latter were determined using the Spielberger-Hanin Anxiety Self-Esteem scale. Results. The patients with AF who had experienced CES were noted to have high BP variability associated with increased RA and PA scores. Group 1 showed statistically significant improvements in RA and PA 2 and 6 weeks after the start of treatment. The efficiency of anti-anxiety therapy (adaptol at a dose of 500 to 1500 mg/day) in combination with antihypertensive drugs is confirmed by the normalized circadian BP profile. Conclusion. The incorporation of an anxiolytic into pharmacotherapy regimens could improve BP, namely, to reduce and stabilize its circadian profile.
作者简介
I Zolotovskaya
ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава РоссииСамара, Россия
I Davydkin
ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава РоссииСамара, Россия
I Poverennova
ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава РоссииСамара, Россия
参考
- Chowdhury EK, Owen A, Krum H, Wing LM, Nelson M, Reid CM. Second Australian National Blood Pressure Study Management Committee. Systolic blood pressure variability is an important predictor of cardiovascular outcomes in elderly hypertensive patients. J Hypertens. 2014;32(3):525-533. https://doi.org/10.1097/hjh.0000000000000028
- Muntner P, Booth JN, Shimbo D, Schwartz JE. Is white-coat hypertension associated with increased cardiovascular and mortality risk? J Hypertens. 2016;34(8):1655-1658. https://doi.org/10.1097/hjh.0000000000000983
- Vishram JK, Dahlöf B, Devereux RB, Ibsen H, Kjeldsen SE, Lindholm LH, Mancia G, Okin PM, Rothwell PM, Wachtell K, Olsen MH. Blood pressure variability predicts cardiovascular events independently of traditional cardiovascular risk factors and target organ damage: a LIFE substudy. J Hypertens. 2015;33(12): 2422-2430. https://doi.org/10.1097/hjh.0000000000000739
- Manning LS, Rothwell PM, Potter JF, Robinson TG. Prognostic Significance of Short-Term Blood Pressure Variability in Acute Stroke: Systematic Review. Stroke. 2015;46(9):2482-2490. https://doi.org/10.1161/strokeaha.115.010075
- Lau KK, Wong YK, Teo KC, Chang R., Chan KH, Hon SF, Wat KL, Cheung RT, Li LS, Siu CW, Tse HF. Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischemic stroke. Am J Hypertens. 2014;27:1486-1494. https://doi.org/10.1093/ajh/hpu070
- Золотовская И.А., Давыдкин И.Л., Дупляков Д.В. Впервые диагностированная инсульт-ассоциированная фибрилляция предсердий: риски развития неблагоприятных клинических исходов (результаты субанализа когортного исследования АПОЛЛОН). Архивъ внутренней медицины. 2017;7(5):364-370.
- Tedla YG, Yano Y, Carnethon M, Greenland P. Association Between Long-Term Blood Pressure Variability and 10-Year Progression in Arterial Stiffness: The Multiethnic Study of Atherosclerosis. Hypertension. 2017;69(1):118-127. https://doi.org/10.1161/hypertensionaha.116.08427
- Tanaka S, Masuda T, Kamiya K, Hamazaki N, Akiyama A, Kamada Y, Maekawa E, Noda C, Yamaoka-Tojo M, Ako J. A Single Session of Neuromuscular Electrical Stimulation Enhances Vascular Endothelial Function and Peripheral Blood Circulation in Patients With Acute Myocardial Infarction. Int Heart J. 2016;57(6):676-681. https://doi.org/10.1536/ihj.15-493
- Proietti M, Romiti GF, Olshansky B, Lip GYH. Systolic Blood Pressure Visit-to-Visit Variability and Major Adverse Outcomes in Atrial Fibrillation: The AFFIRM Study (Atrial Fibrillation Follow-Up Investigation of Rhythm Management). Hypertension. 2017;70(5):949-958. https://doi.org/10.1161/hypertensionaha.117.10106
- Wu D, Li C, Chen Y, Xiong H, Tian X, Wu W, Huang W, Zhang YT, Zhang H. Influence of blood pressure variability on early carotid atherosclerosis in hypertension with and without diabetes. Medicine (Baltimore). 2016;95(24):e3864. https://doi.org/10.1097/md.0000000000003864
- Tully PJ, Tzourio C. Psychiatric correlates of blood pressure variability in the elderly: The Three City cohort study. Physiol Behav. 2017;168:91-97. https://doi.org/10.1016/j.physbeh.2016.10.024
- Wändell P, Carlsson AC, Gasevic D, Wahlström L, Sundquist J, Sundquist K. Depression or anxiety and all-cause mortality in adults with atrial fibrillation — A cohort study in Swedish primary care. Ann Med. 2016;48(1-2):59-66. https://doi.org/10.3109/07853890.2015.1132842
- Шальнова С.А., Евстифеева С.Е., Деев А.Д., Артамонова Г.В, Гатагонова Т.М., Дупляков Д.В., Ефанов А.Ю., Жернакова Ю.В., Конради А.О., Либис Р.А., Минаков Э.В., Недогода С.В., Ощепкова Е.В., Романчук С.В., Ротарь О.П., Трубачева И.А., Шляхто Е.В., Бойцов С.А. От имени участников исследования ЭССЕ-РФ. Распространенность тревоги и депрессии в различных регионах Российской Федерации и ее ассоциации с социально-демографическими факторами (по данным исследования ЭССЕ-РФ. Терапевтический архив. 2014;(12):52-59. https://doi.org/10.17116/terarkh2014861253-60
- Чазов Е.И., Оганов Р.Г., Погосова Г.В., Шальнова С.А., Ромасенко А.В., Деев А.Д. Клинико-эпидемиологическая программа изучения депрессий в кардиологической практике: у больных артериальной гипертонией и ишемической болезнью сердца (КООРДИНАТА): результаты многоцентрового исследования. Кардиология. 2007;3:28-37.
- Чазова И.Е., Фомин В.В., Разуваева М.А. Резистентная и неконтролируемая артериальная гипертензия: проблема XXI века. Фарматека. 2011;5:8-13.
- Patel D, McConkey ND, Sohaney R, McNeil A, Jedrzejczyk A, Armaganijan L. A systematic review of depression and anxiety in patients with atrial fibrillation: the mind-heart link. Cardiovascular Psychiatry and Neurology. 2013;2013:159850. https://doi.org/10.1155/2013/159850
- Tanaka E, Koga M, Kobayashi J, Kario K, Kamiyama K, Furui E, Shiokawa Y, Hasegawa Y, Okuda S, Todo K, Kimura K, Okada Y, Okata T, Arihiro S, Sato S, Yamagami H, Nagatsuka K, Minematsu K, Toyoda K. Blood pressure variability on antihypertensive therapy in acute intracerebral hemorrhage: the stroke acute management with urgent risk-factor assessment and improvement-intracerebral hemorrhage study. Stroke. 2014;45(8):2275-2279. https://doi.org/10.1161/strokeaha.114.005420
- Chang TI, Reboussin DM, Chertow GM, Cheung AK, Cushman WC, Kostis WJ, Parati G, Raj D, Riessen E, Shapiro B, Stergiou GS, Townsend RR, Tsioufis K, Whelton PK, Whittle J, Wright JT, Papademetriou V; SPRINT Research Group. Visit-to-visit office blood pressure variability and cardiovascular outcomes in SPRINT (Systolic Blood Pressure Intervention Trial). Hypertension. 2017;70(4):751-758. https://doi.org/10.1161/hypertensionaha.117.09788
- Lau KK, Wong YK, Teo KC, Chang RS, Chan KH, Hon SF, Wat KL, Cheung RT, Li LS, Siu CW, Tse HF. Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischemic stroke. Am J Hypertens. 2014;27(12):1486-1494. https://doi.org/10.1093/ajh/hpu070
- Whaley-Connell A, Sowers JR. Metabolic Control of blood pressure variability in humans. J Clin Hypertens (Greenwich). 2016;18(1):25-26. https://doi.org/10.1111/jch.12686
- Давыдкин И.Л., Золотовская И.А. Прогностическое значение суточного мониторирования артериального давления у пациентов с фибрилляцией предсердий, перенесших кардиоэмболический инсульт. Артериальная гипертензия. 2016; 22(1):32-40.
- Золотовская И.А., Давыдкин И.Л., Повереннова И.Е. Современная фармакокоррекция расстройств вегетативной нервной системы. Журнал неврологии и психиатрии им.C.C. Корсакова.2015;115(10-2): 28-30.