Clinicopathogenetic variants of anemia in patients with intestinal inflammation

Vladimir Nikolaevich Drozdov; Дроздов Владимир Николаевич; Al'bina Aleksandrovna Lishchinskaya; Лищинская Альбина Александровна; Asfol'd Ivanovich Parfenov; Парфенов Асфольд Иванович; Karina Kadievna Noskova; Носкова Карина Кадиевна; Irina Nikolaevna Ruchkina; Ручкина Ирина Николаевна; Galina Grigor'evna Varvanina; Варванина Галина Григорьевна; Elena Viktorovna Tkachenko; Ткаченко Елена Викторовна; V N Drozdov; Drozdov V N; A A Lischinskaya; Lischinskaya A A; A I Parfenov; Parfenov A I; K K Noskova; Noskova K K; I N Ruchkina; Ruchkina I N; G G Varvanina; Varvanina G G; E V Tkachenko; Tkachenko E V

Clinicopathogenetic variants of anemia in patients with intestinal inflammation

作者: Drozdov V.N.¹, Lishchinskaya A.A.¹, Parfenov A.I.¹, Noskova K.K.¹, Ruchkina I.N.¹, Varvanina G.G.¹, Tkachenko E.V.¹, Drozdov VN², Lischinskaya AA², Parfenov AI², Noskova KK², Ruchkina IN², Varvanina GG², Tkachenko EV²
隶属关系:
1. Центральный научно-исследовательский институт гастроэнтерологии ДЗ Москвы
2. Central Research Institute of Gastroenterology, Moscow
期: 卷 84, 编号 2 (2012)
页面: 36-41
栏目: Editorial article
URL: https://journals.rcsi.science/0040-3660/article/view/30988
ID: 30988

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Aim. To study factors of anemia pathogenesis in patients with ulcerative colitis (UC) and Crohn's disease (CD).
Material and methods. A total of 80 patients (56% males and 44% females, mean age 39±15.8 years) with UC and CD were divided into two groups: group 1 - 40 patients with anemia; group 2 - 40 controls free of anemia with the same gender characteristics. The examination protocol included: total blood count, parameters of iron metabolism ( TIBC, LIBC, transferrin saturation with iron, ferritin, transferring, etc.), the levels of erythropoietin, C-reactive protein, TNF-alpha, hepsidin, vitamin B12, folic acid.
Results. Group 1 patients had a significantly lower mean level of iron in the blood and transferrin saturation with iron while the other parameters of iron metabolism (TIBC, LIBC, transferrin, ferritin) did not significantly differ from these of group 2.
Conclusion. Anemia in intestinal inflammation is an independent disease with complicated pathogenesis. This demands complete examination of such patients to prescribe adequate combined treatment of anemia with consideration of all pathogenetic factors of its development.

关键词

intestinal inflammatory diseases, Crohn's disease, ulcerative colitis, anemia, ferritin, transferrin, hepsidin, erythropoietin, vitamin B12, folic acid

参考

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Clinicopathogenetic variants of anemia in patients with intestinal inflammation

全文:

详细

关键词

作者简介

Vladimir Drozdov

Al'bina Lishchinskaya

Asfol'd Parfenov

Karina Noskova

Irina Ruchkina

Galina Varvanina

Elena Tkachenko

V Drozdov

A Lischinskaya

A Parfenov

K Noskova

I Ruchkina

G Varvanina

E Tkachenko

参考

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