Patent foramen ovale as the cause of recurrent embolic strokes. Case report
- 作者: Komarov A.1, Krivosheeva E.1, Makeev M.1, Merkulov E.1, Tripoten M.1, Panchenko E.1
-
隶属关系:
- Chazov National Medical Research Center of Cardiology
- 期: 卷 94, 编号 9 (2022)
- 页面: 1109-1114
- 栏目: Clinical notes
- URL: https://journals.rcsi.science/0040-3660/article/view/112060
- DOI: https://doi.org/10.26442/00403660.2022.09.201842
- ID: 112060
如何引用文章
全文:
详细
А clinical case of a young patient with recurrent ischemic strokes is presented. The problems of diagnostic embolic strokes are discussed. We set out the algorithm for identifying patients, in whom patent foramen ovale is the most probable cause of embolic stroke. Detailed consideration of imaging diagnostic methods possibility is included. Hypothesis of probable source of cardioembolism from patent foramen ovale is presented. Recommendations for the secondary prevention of recurrent ischemic stroke, associated with patent foramen ovale, are provided. We also considered the issues of antithrombotic treatment.
作者简介
Andrey Komarov
Chazov National Medical Research Center of Cardiology
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0001-9141-103X
д-р мед. наук, вед. науч. сотр. отд. клинических проблем атеротромбоза
俄罗斯联邦, MoscowElena Krivosheeva
Chazov National Medical Research Center of Cardiology
编辑信件的主要联系方式.
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0003-1146-9974
канд. мед. наук, мл. науч. сотр. отд. клинических проблем атеротромбоза
俄罗斯联邦, MoscowMaksim Makeev
Chazov National Medical Research Center of Cardiology
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0002-4779-5088
врач ультразвуковой диагностики
俄罗斯联邦, MoscowEvgeny Merkulov
Chazov National Medical Research Center of Cardiology
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0001-8193-8575
д-р мед. наук, ст. науч. сотр., зав. отд-нием рентгенэндоваскулярных методов диагностики и лечения
俄罗斯联邦, MoscowMaria Tripoten
Chazov National Medical Research Center of Cardiology
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0003-4462-3894
канд. мед. наук, науч. сотр., врач ультразвуковой диагностики отд-ния ультразвуковой диагностики
俄罗斯联邦, MoscowElizaveta Panchenko
Chazov National Medical Research Center of Cardiology
Email: lena-4ka@yandex.ru
ORCID iD: 0000-0002-1174-2574
д-р мед. наук., проф., рук-ль отд. клинических проблем атеротромбоза
俄罗斯联邦, Moscow参考
- Béjot Y, Bailly H, Durier J, Giroud M. Epidemiology of stroke in Europe and trends for the 21st century. La Presse Médicale. 2016;45(12):e391-8. doi: 10.1016/j.lpm.2016.10.003
- Virani S, Alonso A, Benjamin E, et al. Heart Disease and Stroke Statistics – 2020 Update: A Report From the American Heart Association. Circulation. 2020;141(9):e139-596. doi: 10.1161/cir.0000000000000757
- Акжигитов Р.Г., Алекян Б.Г., Алферова В.В., и др. Клинические рекомендации. Ишемический инсульт и транзиторная ишемичес- кая атака у взрослых. М.: Атомиздат, 2021. Режим доступа: https://www.neurology.ru/klinicheskie-rekomendacii-ishemicheskiy-insult-i-tranzitornaya-ishemicheskaya-ataka-u-vzroslyh. Ссылка активна на 11.09.2022 [Akzhigitov RG, Alekian BG, Alferova VV, et al. Klinicheskie rekomendatsii. Ishemicheskii insul't i tranzitornaia ishemicheskaia ataka u vzroslykh. Moscow: Atomizdat, 2021. Available at: https://www.neurology.ru/klinicheskie-rekomendacii-ishemicheskiy-insult-i-tranzitornaya-ishemicheskaya-ataka-u-vzroslyh. Accessed: 11.09.2022 (in Russian)].
- Adams H, Bendixen B, Kappelle L, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35-41. doi: 10.1161/01.str.24.1.35
- Kleindorfer D, Towfighi A, Chaturvedi S, et al. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2021;52(7):e364-e467. doi: 10.1161/str.0000000000000375
- Hart R, Diener H, Coutts S, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurology. 2014;13(4):429-38. doi: 10.1016/s1474-4422(13)70310-7
- Ntaios G, Perlepe K, Lambrou D, et al. Prevalence and Overlap of Potential Embolic Sources in Patients With Embolic Stroke of Undetermined Source. J Am Heart Assoc. 2019;8(15):e012858. doi: 10.1161/jaha.119.012858
- Ahmed N, Audebert H, Turc G, et al. Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11–13 November 2018. Eur Stroke J. 2019;4(4):307-17. doi: 10.1177/2396987319863606
- Hart R, Catanese L, Perera K, et al. Embolic Stroke of Undetermined Source. Stroke. 2017;48(4):867-72. doi: 10.1161/strokeaha.116.016414
- Hart R, Sharma M, Mundl H, et al. Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source. N Engl J Med. 2018;378(23):2191-201. doi: 10.1056/nejmoa1802686
- Ntaios G, Papavasileiou V, Milionis H, et al. Embolic Strokes of Undetermined Source in the Athens Stroke Registry. Stroke. 2015;46(8):2087-93. doi: 10.1161/strokeaha.115.009334
- Diener H, Sacco R, Easton J, et al. Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. N Engl J Med. 2019;380(20):1906-17. doi: 10.1056/nejmoa1813959
- Toyoda K, Uchiyama S, Hagihara Y, et al. Dabigatran vs. Aspirin for Secondary Prevention After Embolic Stroke of Undetermined Source – Japanese Subanalysis of the RE-SPECT ESUS Randomized Controlled Trial. Circ J. 2020;84(12):2286-95. doi: 10.1253/circj.CJ-20-0563
- Healey J, Gladstone D, Swaminathan B, et al. Recurrent Stroke With Rivaroxaban Compared With Aspirin According to Predictors of Atrial Fibrillation. JAMA Neurol. 2019;76(7):764-73. doi: 10.1001/jamaneurol.2019.0617
- Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2020;42(5):373-498. doi: 10.1093/eurheartj/ehaa612
- Schnabel R, Haeusler K, Healey J, et al. Searching for Atrial Fibrillation Poststroke. Circulation. 2019;140(22):1834-50. doi: 10.1161/circulationaha.119.040267
- Kasner S, Swaminathan B, Lavados P, et al. Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial. Lancet Neurol. 2018;17(12):1053-60. doi: 10.1016/s1474-4422(18)30319-3
- Mojadidi M, Winoker J, Roberts S, et al. Accuracy of Conventional Transthoracic Echocardiography for the Diagnosis of Intracardiac Right-to-Left Shunt: A Meta-Analysis of Prospective Studies. Echocardiography. 2014;31(9):1036-48. doi: 10.1111/echo.12583
- Schnabel R, Camen S, Knebel F, et al. Expert opinion paper on cardiac imaging after ischemic stroke. Clin Res Cardiol. 2021;110(7):938-58. doi: 10.1007/s00392-021-01834-x
- Pristipino C, Sievert H, D'Ascenzo F, et al. European position paper on the management of patients with patent foramen ovale. General approach and left circulation thromboembolism. Eurointervention. 2019;14(13):1389-402. doi: 10.4244/eij-d-18-00622
- Giblett J, Williams L, Kyranis S, et al. Patent Foramen Ovale Closure: State of the Art. Interventional. Interv Cardiol. 2020;15:e15. doi: 10.15420/icr.2019.27
- Kent D, Ruthazer R, Weimar C, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology. 2013;81(7):619-25. doi: 10.1212/wnl.0b013e3182a08d59
- Kent D, Saver J, Ruthazer R, et al. Risk of Paradoxical Embolism (RoPE) – Estimated Attributable Fraction Correlates With the Benefit of Patent Foramen Ovale Closure. Stroke. 2020;51(10):3119-23. doi: 10.1161/strokeaha.120.029350
- Mojadidi M, Bogush N, Caceres J, et al. Diagnostic Accuracy of Transesophageal Echocardiogram for the Detection of Patent Foramen Ovale: A Meta-Analysis. Echocardiography. 2013;31(6):752-8. doi: 10.1111/echo.12462
- Mojadidi M, Roberts S, Winoker J, et al. Accuracy of Transcranial Doppler for the Diagnosis of Intracardiac Right-to-Left Shunt. JACC Cardiovascular Imaging. 2014;7(3):236-50. doi: 10.1016/j.jcmg.2013.12.011
- Yan C, Li H. Preliminary Investigation of In situ Thrombus Within Patent Foramen Ovale in Patients With and Without Stroke. JAMA. 2021;325(20):2116. doi: 10.1001/jama.2021.4359
- Hakeem A, Cilingiroglu M, Katramados A, et al. Transcatheter closure of patent foramen ovale for secondary prevention of ischemic stroke: Quantitative synthesis of pooled randomized trial data. Catheter Cardiovasc Interv. 2018;92(6):1153-60. doi: 10.1002/ccd.27487
- Turc G, Calvet D, Guérin P, et al. Closure, Anticoagulation, or Antiplatelet Therapy for Cryptogenic Stroke With Patent Foramen Ovale: Systematic Review of Randomized Trials, Sequential Meta-Analysis, and New Insights From the CLOSE Study. J Am Heart Assoc. 2018;7(12):e008356. doi: 10.1161/jaha.117.008356