Chronic thromboembolic pulmonary hypertension: from pathogenesis to the choice of treatment tactics
- 作者: Valieva Z.1, Martynyuk T.1,2
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隶属关系:
- Chazov National Medical Research Center of Cardiology
- Pirogov Russian National Research Medical University
- 期: 卷 94, 编号 7 (2022)
- 页面: 791-796
- 栏目: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/109635
- DOI: https://doi.org/10.26442/00403660.2022.07.201741
- ID: 109635
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Presents data on the pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH), which serve as a rationale for approaches to the choice of treatment. CTEPH usually begins with persistent obstruction of the large and/or medium pulmonary arteries by organized thrombi. Impaired lysis of thrombi may be associated with abnormal fibrinolysis, hematological or autoimmune diseases. The molecular processes underlying the lesions of small vessels are not fully understand. The degree of small-vessel disease has a significant impact on the severity of CTEPH and postoperative outcomes. The CTEPH treatment has evolved with the development of three directions – pulmonary endarterectomy, balloon angioplasty of pulmonary arteries and the use of specific therapy used for pulmonary arterial hypertension. The paper demonstrates the possibilities of a multimodal approach in the treatment of this category of patients.
作者简介
Zarina Valieva
Chazov National Medical Research Center of Cardiology
编辑信件的主要联系方式.
Email: v.zarina.v@gmail.com
ORCID iD: 0000-0002-9041-3604
канд. мед. наук, ст. науч. сотр. отд. легочной гипертензии и заболеваний сердца
俄罗斯联邦, MoscowTamila Martynyuk
Chazov National Medical Research Center of Cardiology; Pirogov Russian National Research Medical University
Email: trukhiniv@mail.ru
ORCID iD: 0000-0002-9022-8097
д-р мед. наук, рук. отд. легочной гипертензии и заболеваний сердца; проф. каф. кардиологии фак-та дополнительного профессионального образования
俄罗斯联邦, Moscow; Moscow参考
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