ACTIV SARS-CoV-2 registry (Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients). Assessment of impact of combined original comorbid diseases in patients with COVID-19 on the prognosis
- Authors: Arutyunov G.P.1,2, Tarlovskaya E.I.1,3, Arutyunov A.G.1,2, Belenkov Y.N.4, Konradi A.O.5, Lopatin Y.M.6, Rebrov A.P.7, Tereshchenko S.N.8, Chesnikova A.I.9, Hayrapetyan H.G.10, Babin A.P.11, Bakulin I.G.12, Bakulina N.V.12, Balykova L.A.13, Blagonravova A.S.3, Boldina M.V.3, Vaisberg A.R.3, Galyavich A.S.14,15, Gomonova V.V.12, Grigorieva N.Y.16, Gubareva I.V.17, Demko I.V.18, Evzerikhina A.V.19, Zharkov A.V.20, Kamilova U.K.21, Kim Z.F.22, Kuznetsova T.Y.23, Lareva N.V.24, Makarova E.V.3, Malchikova S.V.25, Nedogoda S.V.6, Petrova M.M.26, Pochinka I.G.3,27, Protasov K.V.28, Protsenko D.N.29, Ruzanau D.Y.30, Sayganov S.A.12, Sarybaev A.S.31, Selezneva N.M.13, Sugraliev A.B.32, Fomin I.V.3, Khlynova O.V.33, Chizhova O.Y.12, Shaposhnik I.I.34, Sh'ukarev D.A.20, Abdrahmanova А.K.35,36, Avetisian S.A.10, Avoyan H.G.10, Azarian K.K.10, Aimakhanova G.T.32, Ayipova D.A.31, Akunov A.C.31, Alieva M.K.12, Aparkina A.V.37, Aruslanova O.R.38, Ashina E.Y.3, Badina O.Y.39, Barisheva O.Y.23, Batchayeva A.S.2, Bitieva A.M.12, Bikhteyev I.U.12, Borodulina N.A.38, Bragin M.V.12, Budu A.M.40, Bykova G.M.33, Vagapova K.R.41, Varlamova D.D.23, Vezikova N.N.23, Verbitskaya E.A.26, Vilkova O.E.16, Vinnikova E.A.12, Vustina V.V.42, Galova E.A.3, Genkel V.V.34, Gorshenina E.I.13, Gostishev R.V.29, Grigorieva E.V.7, Gubareva E.Y.17, Dabylova G.M.32, Demchenko A.I.17, Dolgikh O.Y.43, Duyshobayev M.Y.31, Evdokimov D.S.12, Egorova K.E.44, Ermilova A.N.1,45, Zheldybayeva A.E.32, Zarechnova N.V.39, Zimina Y.D.46, Ivanova S.Y.47, Ivanchenko E.Y.3, Ilina M.V.48, Kazakovtseva M.V.25, Kazymova E.V.49, Kalinina Y.S.26, Kamardina N.A.39, Karachenova A.M.50, Karetnikov I.A.51, Karoli N.A.7, Karsiev M.K.12, Кaskaeva D.S.26, Kasymova K.F.26, Kerimbekova Z.B.31, Kerimova A.S.29, Kim E.S.15,22, Kiseleva N.V.3, Klimenko D.A.17, Klimova A.V.52,2, Kovalishena O.V.3, Kolmakova E.V.12, Kolchinskaya T.P.40, Kolyadich M.I.34,40, Kondriakova O.V.17, Konoval M.P.12, Konstantinov D.Y.17, Konstantinova E.A.17, Kordukova V.A.3, Koroleva E.V.53, Kraposhina A.Y.18,26, Kriukova T.V.54, Kuznetsova A.S.34, Kuzmina T.Y.26, Kuzmichev K.V.55, Kulchoroevna C.K.31, Kuprina T.V.23, Kouranova I.M.56, Kurenkova L.V.57, Kurchugina N.Y.17, Kushubakova N.A.58, Levankova V.I.59, Lyubavina N.A.3, Magdeyeva N.A.37, Mazalov K.V.39, Majseenko V.I.30, Makarova A.S.28, Maripov A.M.31, Marusina A.A.48, Melnikov E.S.1,12, Moiseenko N.B.16, Muradova F.N.3, Muradyan R.G.60, Musaelian S.N.61, Myshak A.O.62, Nekaeva E.S.3, Nikitina N.M.37, Ogurlieva B.B.2,63, Odegova A.A.25, Omarova Y.V.3, Omurzakova N.A.58, Ospanova S.O.32, Pahomova E.V.64, Petrov L.D.65, Plastinina S.S.3, Pogrebetskaya V.A.66, Polyakov D.S.3, Ponomarenko E.V.67, Popova L.L.17, Prokofeva N.A.12, Pudova I.A.3,68, Rakov N.A.3, Rahimov A.N.21, Rozanova N.A.69, Serikbolkyzy S.32, Simonov A.A12, Skachkova V.V.42, Soloveva D.V.3, Soloveva I.A.18,26, Subbotin A.K.39, Sukhomlinova I.M.47, Sushilova A.G.12, Tagayeva D.R.21, Titojkina Y.V.13, Tikhonova E.P.26, Tokmin D.S.70, Tolmacheva A.A.71,72, Torgunakova M.S.26, Trenogina K.V.42, Trostianetckaia N.A.12, Trofimov D.A.15,22, Tulichev A.A.3,73, Tursunova A.T.32, Ulanova N.D.55, Fatenkov O.V.17, Fedorishina O.V.28, Fil T.S.12, Fomina I.Y.3,74, Fominova I.S.13, Frolova I.A.39, Tsvinger S.M.75, Tsoma V.V.6, Cholponbaeva M.B.58, Chudinovskikh T.I.25, Shevchenko O.A.76, Sheshina T.V.16, Shishkina E.A.77, Shishkov K.Y.17, Sherbakov S.Y.78, Yausheva E.A.13
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Affiliations:
- Eurasian Association of Therapists
- Pirogov Russian National Research Medical University
- Privolzhsky Research Medical University
- Sechenov First Moscow State Medical University (Sechenov University)
- Almazov National Medical Research Centre
- Volgograd State Medical University
- Saratov State Medical University named after V.I. Razumovsky
- National Medical Research Center of Cardiology
- Rostov State Medical University
- "Erebouni" Cardiology Center
- Nicolae Testemitanu State University of Medicine and Pharmacy
- Mechnikov North-Western State Medical University
- Ogarev Mordovia State University
- Republican Center for Cardiovascular Diseases of Interregional Clinical Diagnostic Center
- Kazan State Medical University
- Lobachevsky State University
- Samara State Medical University
- Regional Clinical Hospital
- Krasnogorsk City Hospital №1
- Kirovsk Interdisrict Hospital
- Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
- City Clinical Hospital №7
- Petrozavodsk State University
- Chita State Medical Academy
- Kirov State Medical University
- Voino-Yasenetsky Krasnoyarsk State Medical University
- City Clinical Hospital №13 of
- Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuous Professional Education
- Moscow City Clinical Hospital №40
- Gomel State Medical University
- Mirrakhimov National Center of Cardiology and Therapy
- Asfendiyarov Kazakh National Medical University
- Vagner Perm State Medical University
- South Ural State Medical University
- Kazakh Medical University of Continuing Education
- Zhekenovа City Clinical Infectious Diseases Hospital
- Razumovsky Saratov State Medical University
- Clinical Cardiological Dispensary
- The Volga District Medical Centre
- City Clinical Hospital №1
- Polyclinic №1 of the President of the Russian Federation
- Perm Regional Clinical Hospital
- Chapaevskaya Central City Hospital
- Baranov Republic Hospital
- Serbsky National Medical Research Centre for Psychiatry and Narcology
- City Clinical Hospital №25
- Hospital for Veterans
- Polyclinic of Kirovsk Interdistrict Hospital
- Clinical Hospital RZhD Meditsyna
- Chita State Medical Academy, Chita
- Irkutsk Regional Сlinical Рospital
- Moscow City State Outpatient Hospital №134
- City Сlinical Рospital №5
- Association "Eurasian Association of Therapists"
- City Clinical Hospital №13 of Nizhnii Novgorod
- Gorodetskaya Central District Hospital
- Katkov Republic Clinical Hospital
- National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
- City Polyclinic №1
- Global Medical System Clinics and Hospitals
- Yerevan State Medical University
- Group of companies "Medinvestgroup"
- Moscow City Clinical Hospital №4
- Republican tuberculosis dispensary
- Health Center of Brichen
- City Clinical Hospital №38
- Medical center "Zimamed"
- Nizhniy Novgorod city Outpatient Hospital №4
- Krasnogorsk city hospital №1
- Labs of the Future
- Novosibirsk State Medical University
- Clinical Counselling and Diagnostic Polyclinic
- SBHI of Nizhniy Novgorod region City Clinical Hospital №3
- SBHI of Nizhniy Novgorod region City Outpatient Hospital №1
- Chita State Medical Academy of Medicine
- Samara City Polyclinic №3
- Perm State Medical University named after E.A. Vagner
- Kazan State Medical Academy – Branch of the Russian Medical Academy of Continuous Professional Education
- Issue: Vol 94, No 1 (2022)
- Pages: 32-47
- Section: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/71639
- DOI: https://doi.org/10.26442/00403660.2022.01.201320
- ID: 71639
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Abstract
Aim. Study the impact of various combinations of comorbid original diseases in patients infected with COVID-19 later on the disease progression and outcomes of the new coronavirus infection.
Materials and methods. The ACTIV registry was created on the Eurasian Association of Therapists’ initiative. 5,808 patients have been included in the registry: men and women with COVID-19 treated at hospital or at home. ClinicalTrials.gov ID NCT04492384.
Results. Most patients with COVID-19 have original comorbid diseases (oCDs). Polymorbidity assessed by way of simple counting of oCDs is an independent factor in negative outcomes of COVID-19. Search for most frequent combinations of 2, 3 and 4 oCDs has revealed absolute domination of cardiovascular diseases (all possible variants). The most unfavorable combination of 2 oCDs includes atrial hypertension (AH) and chronic heart failure (CHF). The most unfavorable combination of 3 oCDs includes AH, coronary heart disease (CHD) and CHF; the worst combination of 4 oCDs includes AH, CHD, CHF and diabetes mellitus. Such combinations increased the risk of lethal outcomes 3.963, 4.082 and 4.215 times respectively.
Conclusion. Polymorbidity determined by way of simple counting of diseases may be estimated as a factor in the lethal outcome risk in the acute phase of COVID-19 in real practice. Most frequent combinations of 2, 3 and 4 diseases in patients with COVID-19 primarily include cardiovascular diseases (AH, CHD and CHF), diabetes mellitus and obesity. Combinations of such diseases increase the COVID-19 lethal outcome risk.
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##article.viewOnOriginalSite##About the authors
Gregory P. Arutyunov
Eurasian Association of Therapists; Pirogov Russian National Research Medical University
Email: arut@ossn.ru
ORCID iD: 0000-0002-6645-2515
Russian Federation, Moscow; Moscow
Ekaterina I. Tarlovskaya
Eurasian Association of Therapists; Privolzhsky Research Medical University
Email: etarlovskaya@mail.ru
ORCID iD: 0000-0002-9659-7010
д-р мед. наук, проф., Ассоциация ЕАТ, зав. каф. терапии и кардиологии
Russian Federation, Moscow; Nizhnii NovgorodAlexander G. Arutyunov
Eurasian Association of Therapists; Pirogov Russian National Research Medical University
Email: agarutyunov@mail.ru
ORCID iD: 0000-0003-1180-3549
Russian Federation, Moscow; Moscow
Yuri N. Belenkov
Sechenov First Moscow State Medical University (Sechenov University)
Email: ynbelenkov@gmail.com
ORCID iD: 0000-0002-6180-2619
Russian Federation, Moscow
Alexandra O. Konradi
Almazov National Medical Research Centre
Email: konradi@almazovcentre.ru
ORCID iD: 0000-0001-8169-7812
Russian Federation, Saint Petersburg
Yury M. Lopatin
Volgograd State Medical University
Email: prof_lopatin@mail.ru
ORCID iD: 0000-0003-1943-1137
Russian Federation, Volgograd
Andrey P. Rebrov
Saratov State Medical University named after V.I. Razumovsky
Email: andreyrebrov@yandex.ru
ORCID iD: 0000-0002-3463-7734
Russian Federation, Saratov
Sergey N. Tereshchenko
National Medical Research Center of Cardiology
Email: stereschenko@yandex.ru
ORCID iD: 0000-0001-9234-6129
Russian Federation, Moscow
Anna I. Chesnikova
Rostov State Medical University
Email: rostov-ossn@yandex.ru
ORCID iD: 0000-0002-9323-592X
Russian Federation, Rostov-on-Don
Hamlet G. Hayrapetyan
"Erebouni" Cardiology Center
Email: Cardioerebouni@yahoo.com
ORCID iD: 0000-0002-8764-5623
Armenia, Yerevan
Aleksandr P. Babin
Nicolae Testemitanu State University of Medicine and Pharmacy
Email: alexababin@rambler.ru
Moldova, Republic of, Chisinau
Igor G. Bakulin
Mechnikov North-Western State Medical University
Email: igbakulin@yandex.ru
ORCID iD: 0000-0002-6151-2021
Russian Federation, Saint Petersburg
Natalia V. Bakulina
Mechnikov North-Western State Medical University
Email: nv_bakulina@mail.ru
ORCID iD: 0000-0003-4075-4096
Russian Federation, Saint Petersburg
Larisa A. Balykova
Ogarev Mordovia State University
Email: larisabalykova@yandex.ru
ORCID iD: 0000-0002-2290-0013
Russian Federation, Saransk
Anna S. Blagonravova
Privolzhsky Research Medical University
Email: a.blagonravova@mail.ru
ORCID iD: 0000-0002-1467-049X
Russian Federation, Nizhnii Novgorod
Marina V. Boldina
Privolzhsky Research Medical University
Email: mari.boldina@mail.ru
ORCID iD: 0000-0002-1794-0707
Russian Federation, Nizhnii Novgorod
Alexandra R. Vaisberg
Privolzhsky Research Medical University
Email: a2912v@mail.ru
ORCID iD: 0000-0003-3658-5330
Russian Federation, Nizhnii Novgorod
Albert S. Galyavich
Republican Center for Cardiovascular Diseases of Interregional Clinical Diagnostic Center; Kazan State Medical University
Email: agalyavich@mail.ru
ORCID iD: 0000-0002-4510-6197
Russian Federation, Kazan; Kazan
Veronika V. Gomonova
Mechnikov North-Western State Medical University
Email: veronika.gomonova@szgmu.ru
ORCID iD: 0000-0002-9816-9896
Russian Federation, Saint Petersburg
Natalia Yu. Grigorieva
Lobachevsky State University
Email: grigoreva28@mail.ru
ORCID iD: 0000-0001-6795-7884
Russian Federation, Nizhnii Novgorod
Irina V. Gubareva
Samara State Medical University
Email: irigub@rambler.ru
ORCID iD: 0000-0003-1881-024X
Russian Federation, Samara
Irina V. Demko
Regional Clinical Hospital
Email: demko64@mail.ru
ORCID iD: 0000-0001-8982-5292
Russian Federation, Krasnoiarsk
Angelika V. Evzerikhina
Krasnogorsk City Hospital №1
Email: angelika@ossn.ru
Russian Federation, Krasnogorsk
Aleksandr V. Zharkov
Kirovsk Interdisrict Hospital
Email: al.zharkov@bk.ru
ORCID iD: 0000-0001-6649-0928
Russian Federation, Kirovsk
Umida K. Kamilova
Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Email: umida_kamilova@mail.ru
ORCID iD: 0000-0002-5104-456X
Uzbekistan, Tashkent
Zulfia F. Kim
City Clinical Hospital №7
Email: profz@yandex.ru
ORCID iD: 0000-0003-4240-3329
Russian Federation, Kazan
Tatiana Yu. Kuznetsova
Petrozavodsk State University
Email: eme@karelia.ru
ORCID iD: 0000-0002-6654-1382
Russian Federation, Petrozavodsk
Natalia V. Lareva
Chita State Medical Academy
Email: larevanv@mail.ru
ORCID iD: 0000-0001-9498-9216
Russian Federation, Chita
Ekaterina V. Makarova
Privolzhsky Research Medical University
Email: e_makarowa@mail.ru
ORCID iD: 0000-0003-4394-0687
Russian Federation, Nizhnii Novgorod
Svetlana V. Malchikova
Kirov State Medical University
Email: malchikova@list.ru
ORCID iD: 0000-0002-2209-9457
Russian Federation, Kirov
Sergey V. Nedogoda
Volgograd State Medical University
Email: nedogodasv@mail.ru
ORCID iD: 0000-0001-5981-1754
Russian Federation, Volgograd
Marina M. Petrova
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: stk99@yandex.ru
ORCID iD: 0000-0002-8493-0058
Russian Federation, Krasnoyarsk
Ilya G. Pochinka
Privolzhsky Research Medical University; City Clinical Hospital №13 of
Email: pochinka4@yandex.ru
ORCID iD: 0000-0001-5709-0703
Russian Federation, Nizhnii Novgorod; Nizhnii Novgorod
Konstantin V. Protasov
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuous Professional Education
Email: protassov_k@rambler.ru
ORCID iD: 0000-0002-6516-3180
Russian Federation, Irkutsk
Denis N. Protsenko
Moscow City Clinical Hospital №40
Email: drprotsenko@me.com
ORCID iD: 0000-0002-5166-3280
Russian Federation, Moscow
Dmitry Yu. Ruzanau
Gomel State Medical University
Email: druzanoff@mail.ru
ORCID iD: 0000-0001-5291-4937
Belarus, Gomel
Sergey A. Sayganov
Mechnikov North-Western State Medical University
Email: ssayganov@gmail.com
ORCID iD: 0000-0001-7319-2734
Russian Federation, Saint Petersburg
Akpay S. Sarybaev
Mirrakhimov National Center of Cardiology and Therapy
Email: ak_sar777@mail.ru
ORCID iD: 0000-0003-2172-9776
Kyrgyzstan, Bishkek
Natalia M. Selezneva
Ogarev Mordovia State University
Email: nata_rm@mail.ru
ORCID iD: 0000-0002-3004-2063
Russian Federation, Saransk
Akhmetzhan B. Sugraliev
Asfendiyarov Kazakh National Medical University
Email: Asugraliyev@gmail.com
ORCID iD: 0000-0002-8255-4159
Kazakhstan, Alma-Ata
Igor V. Fomin
Privolzhsky Research Medical University
Email: fomin-i@yandex.ru
ORCID iD: 0000-0003-0258-5279
Russian Federation, Nizhnii Novgorod
Olga V. Khlynova
Vagner Perm State Medical University
Email: olgakhlynova@mail.ru
ORCID iD: 0000-0003-4860-0112
Russian Federation, Perm
Olga Yu. Chizhova
Mechnikov North-Western State Medical University
Email: Ochizhova@gmail.com
ORCID iD: 0000-0002-1716-7654
Russian Federation, Saint Petersburg
Igor I. Shaposhnik
South Ural State Medical University
Email: shaposhnik@yandex.ru
ORCID iD: 0000-0002-7731-7730
Russian Federation, Chelyabinsk
Dmitry A. Sh'ukarev
Kirovsk Interdisrict Hospital
Email: Polkovnik1979@mail.ru
Russian Federation, Kirovsk
Айгуль K. Abdrahmanova
Kazakh Medical University of Continuing Education; Zhekenovа City Clinical Infectious Diseases Hospital
Email: a.kamet@mail.ru
ORCID iD: 0000-0002-6332-9503
Kazakhstan, Alma-Ata; Alma-Ata
Susanna A. Avetisian
"Erebouni" Cardiology Center
Email: Susanna.avetisyan.94@gmail.com
Armenia, Yerevan
Hovhannes G. Avoyan
"Erebouni" Cardiology Center
Email: drhovhannes@gmail.com
ORCID iD: 0000-0002-3335-7255
Armenia, Yerevan
Karine K. Azarian
"Erebouni" Cardiology Center
Email: karina7493@mail.ru
Armenia, Yerevan
Galiya T. Aimakhanova
Asfendiyarov Kazakh National Medical University
Email: aigalka@mail.ru
Kazakhstan, Alma-Ata
Dinara A. Ayipova
Mirrakhimov National Center of Cardiology and Therapy
Email: dinaralievna@gmail.com
Kyrgyzstan, Bishkek
Almazbek Ch. Akunov
Mirrakhimov National Center of Cardiology and Therapy
Email: akunov_almaz@mail.ru
Kyrgyzstan, Bishkek
Marianna K. Alieva
Mechnikov North-Western State Medical University
Email: diezirrhose@gmail.com
ORCID iD: 0000-0002-0763-6111
Russian Federation, Saint Petersburg
Aliona V. Aparkina
Razumovsky Saratov State Medical University
Email: alena437539@yandex.ru
ORCID iD: 0000-0001-8463-2379
Russian Federation, Saratov
Olga R. Aruslanova
Clinical Cardiological Dispensary
Email: cardiolya@mail.ru
ORCID iD: 0000-0002-6974-2614
Russian Federation, Perm
Ekaterina Yu. Ashina
Privolzhsky Research Medical University
Email: ashina.ekaterina@mail.ru
ORCID iD: 0000-0002-7460-2747
Russian Federation, Nizhnii Novgorod
Olga Yu. Badina
The Volga District Medical Centre
Email: badinaolga@yandex.ru
ORCID iD: 0000-0001-9068-8088
Russian Federation, Nizhnii Novgorod
Olga Yu. Barisheva
Petrozavodsk State University
Email: hosptherapy@mail.ru
ORCID iD: 0000-0001-6317-1243
Russian Federation, Petrozavodsk
Alina S. Batchayeva
Pirogov Russian National Research Medical University
Email: empire.al@mail.ru
Russian Federation, Moscow
Anna M. Bitieva
Mechnikov North-Western State Medical University
Email: Anna.Bitieva@szgmu.ru
ORCID iD: 0000-0002-5383-2367
Russian Federation, Saint Petersburg
Ismail U. Bikhteyev
Mechnikov North-Western State Medical University
Email: mr.izmail@mail.ru
ORCID iD: 0000-0003-0663-3549
Russian Federation, Saint Petersburg
Nataliya A. Borodulina
Clinical Cardiological Dispensary
Email: borodulinanataliya@mail.ru
ORCID iD: 0000-0003-1107-5772
Russian Federation, Perm
Maksim V. Bragin
Mechnikov North-Western State Medical University
Email: bragin.max2013@yandex.ru
ORCID iD: 0000-0003-2308-4887
Russian Federation, Saint Petersburg
Angela M. Budu
City Clinical Hospital №1
Email: angela.buduu@gmail.com
Moldova, Republic of, Chisinau
Galina M. Bykova
Vagner Perm State Medical University
Email: vahrushevbl_@mail.ru
ORCID iD: 0000-0003-0823-4605
Russian Federation, Perm
Kristina R. Vagapova
Polyclinic №1 of the President of the Russian Federation
Email: kr.vagapova@mail.ru
Russian Federation, Moscow
Darina D. Varlamova
Petrozavodsk State University
Email: darinavrlm@gmail.com
ORCID iD: 0000-0002-4015-5109
Russian Federation, Petrozavodsk
Natalia N. Vezikova
Petrozavodsk State University
Email: vezikov23@mail.ru
ORCID iD: 0000-0002-8901-3363
Russian Federation, Petrozavodsk
Elena A. Verbitskaya
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: verb.elena2013@yandex.ru
ORCID iD: 0000-0002-5710-7082
Russian Federation, Krasnoiarsk
Olga E. Vilkova
Lobachevsky State University
Email: vilkann@yandex.ru
ORCID iD: 0000-0002-1129-7511
Russian Federation, Nizhnii Novgorod
Elena A. Vinnikova
Mechnikov North-Western State Medical University
Email: lena.vinnikova43@gmail.com
ORCID iD: 0000-0002-5948-1561
Russian Federation, Saint Petersburg
Vera V. Vustina
Perm Regional Clinical Hospital
Email: vustina_vera@mail.ru
ORCID iD: 0000-0003-1466-285X
Russian Federation, Perm
Elena A. Galova
Privolzhsky Research Medical University
Email: Galova75@mail.ru
ORCID iD: 0000-0002-9574-2933
Russian Federation, Nizhnii Novgorod
Vadim V. Genkel
South Ural State Medical University
Email: henkel-07@mal.ru
ORCID iD: 0000-0001-5902-3803
Russian Federation, Chelyabinsk
Elena I. Gorshenina
Ogarev Mordovia State University
Email: Lena.medfak@yandex.ru
Russian Federation, Saransk
Roman V. Gostishev
Moscow City Clinical Hospital №40
Email: gostiroman@gmail.com
ORCID iD: 0000-0002-2379-5761
Russian Federation, Moscow
Elena V. Grigorieva
Saratov State Medical University named after V.I. Razumovsky
Email: lek133@yandex.ru
ORCID iD: 0000-0001-6064-560X
Russian Federation, Saratov
Ekaterina Yu. Gubareva
Samara State Medical University
Email: ekaterina.ju.gubareva@gmail.com
ORCID iD: 0000-0001-6824-3963
Russian Federation, Samara
Gaukhar M. Dabylova
Asfendiyarov Kazakh National Medical University
Email: Goha.doc@mail.ru
Kazakhstan, Alma-Ata
Anastasiya I. Demchenko
Samara State Medical University
Email: nastya.demchenko5741@mail.ru
Russian Federation, Samara
Oleg Yu. Dolgikh
Chapaevskaya Central City Hospital
Email: helpass@yandex.ru
Russian Federation, Chapaevsk
Melis Y. Duyshobayev
Mirrakhimov National Center of Cardiology and Therapy
Email: duishobaev_melis@mail.ru
Kyrgyzstan, Bishkek
Dmitrii S. Evdokimov
Mechnikov North-Western State Medical University
Email: kasabian244@gmail.com
ORCID iD: 0000-0002-3107-1691
Russian Federation, Saint Petersburg
Ksenia E. Egorova
Baranov Republic Hospital
Email: egorovake@mail.ru
ORCID iD: 0000-0003-4233-3906
Russian Federation, Petrozavodsk
Anastasiia N. Ermilova
Eurasian Association of Therapists; Serbsky National Medical Research Centre for Psychiatry and Narcology
Email: stesha_22@mail.ru
ORCID iD: 0000-0002-5704-697X
Russian Federation, Moscow; Moscow
Aliya E. Zheldybayeva
Asfendiyarov Kazakh National Medical University
Email: liya-9090@mail.ru
Kazakhstan, Alma-Ata
Nataliya V. Zarechnova
The Volga District Medical Centre
Email: nvzar@mail.ru
Russian Federation, Nizhnii Novgorod
Yuliia D. Zimina
City Clinical Hospital №25
Email: yulya_tx@mail.ru
ORCID iD: 0000-0001-9027-6884
Russian Federation, Novosibirsk
Svetlana Yu. Ivanova
Hospital for Veterans
Email: nachmed@gvv-rk.ru
ORCID iD: 0000-0002-0720-6621
Russian Federation, Petrozavodsk
Elena Yu. Ivanchenko
Privolzhsky Research Medical University
Email: ivanchenkonino15@yandex.ru
ORCID iD: 0000-0003-4506-1053
Russian Federation, Nizhnii Novgorod
Mariya V. Ilina
Polyclinic of Kirovsk Interdistrict Hospital
Email: mariailina-96@mail.ru
ORCID iD: 0000-0003-2566-1086
Russian Federation, Kirovsk
Maria V. Kazakovtseva
Kirov State Medical University
Email: masha3306@yandex.ru
ORCID iD: 0000-0002-0981-3601
Russian Federation, Kirov
Elena V. Kazymova
Clinical Hospital RZhD Meditsyna
Email: evkazymova@mail.ru
Russian Federation, Samara
Yuliya S. Kalinina
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: kalininajuliya-23111981@mail.ru
ORCID iD: 0000-0001-6037-5857
Russian Federation, Krasnoiarsk
Nadezhda A. Kamardina
The Volga District Medical Centre
Email: n.camardina@yandex.ru
Russian Federation, Nizhnii Novgorod
Anastasiya M. Karachenova
Chita State Medical Academy, Chita
Email: b_a_m_2010@mail.ru
ORCID iD: 0000-0003-1704-490X
Russian Federation, Chita
Igor A. Karetnikov
Irkutsk Regional Сlinical Рospital
Email: karetnikov_ia@iokb.ru
ORCID iD: 0000-0002-0922-6925
Russian Federation, Irkutsk
Nina A. Karoli
Saratov State Medical University named after V.I. Razumovsky
Email: nina.karoli.73@gmail.com
ORCID iD: 0000-0002-7464-826X
Russian Federation, Saratov
Magomed Kh. Karsiev
Mechnikov North-Western State Medical University
Email: magomedkarsiev@gmail.com
ORCID iD: 0000-0002-1794-0694
Russian Federation, Saint Petersburg
Daria S. Кaskaeva
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: dashakas.ru@mail.ru
ORCID iD: 0000-0002-0794-2530
Russian Federation, Krasnoiarsk
Karina F. Kasymova
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: ayaneshiroi@gmail.com
ORCID iD: 0000-0001-8448-6113
Russian Federation, Krasnoiarsk
Zhainagul B. Kerimbekova
Mirrakhimov National Center of Cardiology and Therapy
Email: jaz901@mail.ru
Kyrgyzstan, Bishkek
Ailar Sh. Kerimova
Moscow City Clinical Hospital №40
Email: aylara.kerimova@gmail.com
ORCID iD: 0000-0002-2806-5901
Russian Federation, Moscow
Eugeni S. Kim
Kazan State Medical University; City Clinical Hospital №7
Email: profzh@yandex.ru
Kazan; Kazan
Nina V. Kiseleva
Privolzhsky Research Medical University
Email: ni.na@bk.ru
ORCID iD: 0000-0002-0935-8717
Russian Federation, Nizhnii Novgorod
Darya A. Klimenko
Samara State Medical University
Email: daxik_klim@mail.ru
Russian Federation, Samara
Anastasiia V. Klimova
Moscow City State Outpatient Hospital №134; Pirogov Russian National Research Medical University
Email: an_nikolaychuk@mail.ru
ORCID iD: 0000-0002-3176-7699
Russian Federation, Moscow; Moscow
Olga V. Kovalishena
Privolzhsky Research Medical University
Email: kovalishena@mail.ru
ORCID iD: 0000-0002-9595-547X
Russian Federation, Nizhnii Novgorod
Elena V. Kolmakova
Mechnikov North-Western State Medical University
Email: evkolmakova@mail.ru
Russian Federation, Saint Petersburg
Tatyana P. Kolchinskaya
City Clinical Hospital №1
Email: kamelia-74@mail.ru
Russian Federation, Chelyabinsk
Maria I. Kolyadich
South Ural State Medical University; City Clinical Hospital №1
Email: volchegorsky@gmail.com
ORCID iD: 0000-0002-0168-1480
Russian Federation, Chelyabinsk; Chelyabinsk
Olga V. Kondriakova
Samara State Medical University
Email: aickondryakova@yandex.ru
ORCID iD: 0000-0002-4092-6612
Russian Federation, Samara
Marina P. Konoval
Mechnikov North-Western State Medical University
Email: Marina.Konoval@szgmu.ru
ORCID iD: 0000-0002-8187-6105
Russian Federation, Saint Petersburg
Dmitryi Yu. Konstantinov
Samara State Medical University
Email: dk.samgmu@mail.ru
ORCID iD: 0000-0002-6177-8487
Russian Federation, Samara
Elena A. Konstantinova
Samara State Medical University
Email: e.a.konstantiniva@samsmu.ru
ORCID iD: 0000-0002-6022-0983
Russian Federation, Samara
Vera A. Kordukova
Privolzhsky Research Medical University
Email: ivanovakordukova2373@mail.ru
Russian Federation, Nizhnii Novgorod
Ekaterina V. Koroleva
City Сlinical Рospital №5
Email: katrin.krlv@yandex.ru
Russian Federation, Nizhnii Novgorod
Angelina Yu. Kraposhina
Regional Clinical Hospital; Voino-Yasenetsky Krasnoyarsk State Medical University
Email: angelina-maria@inbox.ru
ORCID iD: 0000-0001-6896-877X
Russian Federation, Krasnoyarsk; Krasnoyarsk
Tamara V. Kriukova
Association "Eurasian Association of Therapists"
Email: tkryukova@euat.ru
Russian Federation, Moscow
Alla S. Kuznetsova
South Ural State Medical University
Email: kuzja321@mail.ru
ORCID iD: 0000-0002-1136-7284
Russian Federation, Chelyabinsk
Tatyana Yu. Kuzmina
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: tkuzmina_24@mail.ru
ORCID iD: 0000-0002-0105-6642
Russian Federation, Krasnoiarsk
Kirill V. Kuzmichev
City Clinical Hospital №13 of Nizhnii Novgorod
Email: krllkzm@gmail.com
Russian Federation, Nizhnii Novgorod
Cholpon K. Kulchoroevna
Mirrakhimov National Center of Cardiology and Therapy
Email: cholpon105@mail.ru
Kyrgyzstan, Bishkek
Tatiana V. Kuprina
Petrozavodsk State University
Email: tanveselova@yandex.ru
ORCID iD: 0000-0002-1176-7309
Russian Federation, Petrozavodsk
Irina M. Kouranova
Gorodetskaya Central District Hospital
Email: kouranova@mail.ru
Russian Federation, Nizhnii Novgorod
Liliya V. Kurenkova
Katkov Republic Clinical Hospital
Email: Kurenkova.lilia@yandex.ru
Russian Federation, Saransk
Natalia Yu. Kurchugina
Samara State Medical University
Email: miss.curchugina@yandex.ru
ORCID iD: 0000-0003-2988-7402
Russian Federation, Samara
Nadira A. Kushubakova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Email: nadira777@mail.ru
ORCID iD: 0000-0001-6874-7125
Kyrgyzstan, Bishkek
Valeriia I. Levankova
City Polyclinic №1
Email: levanlera@yandex.ru
ORCID iD: 0000-0002-0788-4449
Russian Federation, Petrozavodsk
Natalia A. Lyubavina
Privolzhsky Research Medical University
Email: n.lubavina@yandex.ru
ORCID iD: 0000-0002-8914-8268
Russian Federation, Nizhnii Novgorod
Nadezhda A. Magdeyeva
Razumovsky Saratov State Medical University
Email: magnad4@yandex.ru
ORCID iD: 0000-0002-6397-3542
Russian Federation, Saratov
Konstantin V. Mazalov
The Volga District Medical Centre
Email: kvmaz@mail.ru
Russian Federation, Nizhnii Novgorod
Viktoryia I. Majseenko
Gomel State Medical University
Email: vikamaiseenka@gmail.com
ORCID iD: 0000-0003-2133-4360
Belarus, Gomel
Aleksandra S. Makarova
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuous Professional Education
Email: MakarovaAlexandraS@yandex.ru
ORCID iD: 0000-0002-0486-9657
Russian Federation, Irkutsk
Abdirashit M. Maripov
Mirrakhimov National Center of Cardiology and Therapy
Email: r.maripov@mail.ru
ORCID iD: 0000-0003-2801-1994
Kyrgyzstan, Bishkek
Anastasiia A. Marusina
Polyclinic of Kirovsk Interdistrict Hospital
Email: marusina.anastasiya@yandex.ru
ORCID iD: 0000-0002-5301-5746
Russian Federation, Kirovsk
Evgenii S. Melnikov
Eurasian Association of Therapists; Mechnikov North-Western State Medical University
Email: Melnikovzhenya@mail.ru
ORCID iD: 0000-0002-8521-6542
Russian Federation, Moscow; Saint Petersburg
Nikita B. Moiseenko
Lobachevsky State University
Email: nikita00nik00@mail.ru
ORCID iD: 0000-0003-2072-6370
Russian Federation, Nizhnii Novgorod
Fazliniso N. Muradova
Privolzhsky Research Medical University
Email: mfazliniso@list.ru
ORCID iD: 0000-0002-2723-8081
Russian Federation, Nizhnii Novgorod
Rimma G. Muradyan
Global Medical System Clinics and Hospitals
Email: r-virgo@yandex.ru
Russian Federation, Moscow
Shahane N. Musaelian
Yerevan State Medical University
Email: Shahane.musayelyan@gmail.com
Armenia, Yerevan
Anton O. Myshak
Group of companies "Medinvestgroup"
Email: a.myshak@medinvest-group.ru
Russian Federation, Moscow
Ekaterina S. Nekaeva
Privolzhsky Research Medical University
Email: katykur@yandex.com
ORCID iD: 0000-0002-8511-2276
Russian Federation, Nizhnii Novgorod
Nataliia M. Nikitina
Razumovsky Saratov State Medical University
Email: nikina02@yandex.ru
ORCID iD: 0000-0002-0313-1191
Russian Federation, Saratov
Bela B. Ogurlieva
Pirogov Russian National Research Medical University; Moscow City Clinical Hospital №4
Email: Bella_ogurlieva@mail.ru
Russian Federation, Moscow; Moscow
Alla A. Odegova
Kirov State Medical University
Email: all.odegova@yandex.ru
ORCID iD: 0000-0001-9691-6969
Russian Federation, Kirov
Yuliia V. Omarova
Privolzhsky Research Medical University
Email: sailor94mihailova@yandex.ru
ORCID iD: 0000-0002-0942-6070
Russian Federation, Nizhnii Novgorod
Nazgul A. Omurzakova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Email: omurzakova.nazgul@gmail.com
ORCID iD: 0000-0003-3970-9706
Kyrgyzstan, Bishkek
Shynar O. Ospanova
Asfendiyarov Kazakh National Medical University
Email: shynar_oralbayevna@mail.ru
Kazakhstan, Alma-Ata
Ekaterina V. Pahomova
Republican tuberculosis dispensary
Email: katrina15vladimirovna@mail.ru
ORCID iD: 0000-0002-8335-4626
Russian Federation, Syktyvkar
Liviu D. Petrov
Health Center of Brichen
Email: liviu.petrov.60@mail.ru
Moldova, Republic of, Brichen
Svetlana S. Plastinina
Privolzhsky Research Medical University
Email: plastininaswetlana@yandex.ru
ORCID iD: 0000-0002-0534-5986
Russian Federation, Nizhnii Novgorod
Vera A. Pogrebetskaya
City Clinical Hospital №38
Email: mlpu38zamlech@yandex.ru
Russian Federation, Nizhnii Novgorod
Dmitry S. Polyakov
Privolzhsky Research Medical University
Email: dmitriip@mail.ru
ORCID iD: 0000-0001-8421-0168
Russian Federation, Nizhnii Novgorod
Ekaterina V. Ponomarenko
Medical center "Zimamed"
Email: katunya20031991@mail.ru
Russian Federation, Krasnodar
Larisa L. Popova
Samara State Medical University
Email: l.l.popova@samsmu.ru
ORCID iD: 0000-0003-0549-361X
Russian Federation, Samara
Natalya A. Prokofeva
Mechnikov North-Western State Medical University
Email: Natalya.Prokofeva@szgmu.ru
ORCID iD: 0000-0002-7679-413X
Russian Federation, Saint Petersburg
Inna A. Pudova
Privolzhsky Research Medical University; Nizhniy Novgorod city Outpatient Hospital №4
Email: i.a.pudova@yandex.ru
Russian Federation, Nizhniy Novgorod; Nizhniy Novgorod
Nikita A. Rakov
Privolzhsky Research Medical University
Email: vokaratikin@gmail.com
Russian Federation, Nizhnii Novgorod
Abdurakhmon N. Rahimov
Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Email: raximov.a6266@gmail.com
Uzbekistan, Tashkent
Nadezhda A. Rozanova
Krasnogorsk city hospital №1
Email: n_rozanova98@mail.ru
Russian Federation, Krasnogorsk
Saltanat Serikbolkyzy
Asfendiyarov Kazakh National Medical University
Email: Saltanat_1989.89@mail.ru
Kazakhstan, Alma-Ata
Andrei A Simonov
Mechnikov North-Western State Medical University
Email: Andrei.Simonov@szgmu.ru
ORCID iD: 0000-0002-7915-3880
Russian Federation, Saint Petersburg
Valeriya V. Skachkova
Perm Regional Clinical Hospital
Email: valerya1skachkova@yandex.ru
ORCID iD: 0000-0001-7512-2414
Russian Federation, Perm
Daria V. Soloveva
Privolzhsky Research Medical University
Email: dsolow52@yandex.ru
ORCID iD: 0000-0001-5695-0433
Russian Federation, Nizhnii Novgorod
Irina A. Soloveva
Regional Clinical Hospital; Voino-Yasenetsky Krasnoyarsk State Medical University
Email: solovieva.irina@inbox.ru
ORCID iD: 0000-0002-1999-9534
Russian Federation, Krasnoiarsk; Krasnoiarsk
Alexander K. Subbotin
The Volga District Medical Centre
Email: alex_subb@inbox.ru
Russian Federation, Nizhnii Novgorod
Irina M. Sukhomlinova
Hospital for Veterans
Email: sukhomlinova2021@list.ru
Russian Federation, Saint Petersburg
Anastasiia G. Sushilova
Mechnikov North-Western State Medical University
Email: anastasiya.s1311@gmail.com
ORCID iD: 0000-0002-7277-5046
Russian Federation, Saint Petersburg
Dilnoza R. Tagayeva
Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Email: dilnoza_tagaeva@mail.ru
Uzbekistan, Tashkent
Yuliia V. Titojkina
Ogarev Mordovia State University
Email: Julia-titojjkina@yandex.ru
ORCID iD: 0000-0001-9974-359X
Russian Federation, Saransk
Elena P. Tikhonova
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: tihonovaep@mail.ru
ORCID iD: 0000-0001-6466-9609
Russian Federation, Krasnoiarsk
Danil S. Tokmin
Labs of the Future
Email: d.tokmin@ipt-med.ru
Russian Federation, Moscow
Anastasiia A. Tolmacheva
Novosibirsk State Medical University; Clinical Counselling and Diagnostic Polyclinic
Email: tolmacheva_nastena@mail.ru
ORCID iD: 0000-0003-1687-4100
Russian Federation, Novosibirsk; Novosibirsk
Mariya S. Torgunakova
Voino-Yasenetsky Krasnoyarsk State Medical University
Email: mariatorgunakova60875@gmail.com
ORCID iD: 0000-0002-5483-0048
Russian Federation, Krasnoiarsk
Ksenia V. Trenogina
Perm Regional Clinical Hospital
Email: ice_angel20@mail.ru
ORCID iD: 0000-0002-4137-5533
Russian Federation, Perm
Natalia A. Trostianetckaia
Mechnikov North-Western State Medical University
Email: N.Trostyanetckaya@szgmu.ru
Russian Federation, Saint Petersburg
Dmitriy A. Trofimov
Kazan State Medical University; City Clinical Hospital №7
Email: t.dima19961996@gmail.com
ORCID iD: 0000-0001-7613-7132
Russian Federation, Kazan; Kazan
Alexander A. Tulichev
Privolzhsky Research Medical University; SBHI of Nizhniy Novgorod region City Clinical Hospital №3
Email: mr.tulichev@mail.ru
ORCID iD: 0000-0002-3157-2218
Russian Federation, Nizhniy Novgorod; Nizhniy Novgorod
Assiya T. Tursunova
Asfendiyarov Kazakh National Medical University
Email: Atturs1106@mail.ru
Kazakhstan, Alma-Ata
Nina D. Ulanova
City Clinical Hospital №13 of Nizhnii Novgorod
Email: ulanova.nina.1996@yandex.ru
ORCID iD: 0000-0002-5107-6051
Russian Federation, Nizhnii Novgorod
Oleg V. Fatenkov
Samara State Medical University
Email: kdmc@mail.ru
ORCID iD: 0000-0002-4928-5989
Russian Federation, Samara
Olga V. Fedorishina
Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuous Professional Education
Email: olff@mail.ru
ORCID iD: 0000-0002-0155-676X
Russian Federation, Irkutsk
Tatiana S. Fil
Mechnikov North-Western State Medical University
Email: Tatyana.Fil@szgmu.ru
Russian Federation, Saint Petersburg
Irina Yu. Fomina
Privolzhsky Research Medical University; SBHI of Nizhniy Novgorod region City Outpatient Hospital №1
Email: fominadoc@mail.ru
Russian Federation, Nizhniy Novgorod; Nizhniy Novgorod
Irina S. Fominova
Ogarev Mordovia State University
Email: irenebyirishkaa@gmail.com
Russian Federation, Saransk
Irina A. Frolova
The Volga District Medical Centre
Email: frolova-ir@yandex.ru
Russian Federation, Nizhnii Novgorod
Svetlana M. Tsvinger
Chita State Medical Academy of Medicine
Email: tsvinger_s_m@mail.ru
ORCID iD: 0000-0003-2082-9839
Russian Federation, Chita
Vera V. Tsoma
Volgograd State Medical University
Email: vtsoma38@gmail.com
ORCID iD: 0000-0002-0662-1217
Russian Federation, Volgograd
Meerim B. Cholponbaeva
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Email: mercy.venusrich@mail.ru
Kyrgyzstan, Bishkek
Tatiana I. Chudinovskikh
Kirov State Medical University
Email: tanuha_07@mail.ru
ORCID iD: 0000-0002-7515-2215
Russian Federation, Kirov
Olga A. Shevchenko
Samara City Polyclinic №3
Email: chumak063@rambler.ru
Russian Federation, Samara
Tatyana V. Sheshina
Lobachevsky State University
Email: tatiana.sheshina@mail.ru
Russian Federation, Nizhnii Novgorod
Ekaterina A. Shishkina
Perm State Medical University named after E.A. Vagner
Email: doctor.shishkina@yandex.ru
ORCID iD: 0000-0001-6965-7869
Russian Federation, Perm
Konstantin Yu. Shishkov
Samara State Medical University
Email: k.shishkoff@yandex.ru
ORCID iD: 0000-0003-2942-6200
Russian Federation, Samara
Stanislav Yu. Sherbakov
Kazan State Medical Academy – Branch of the Russian Medical Academy of Continuous Professional Education
Email: vnim4nie@yandex.ru
Russian Federation, Kazan
Ekaterina A. Yausheva
Ogarev Mordovia State University
Author for correspondence.
Email: katyayausheva@mail.ru
Russian Federation, Saransk
References
- Идентификатор ClinicalTrials.gov: NCT044923841. [Identifier ClinicalTrials.gov: NCT044923841].
- Richardson S, Hirsch JS, Narasimhan M, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020;323(20):2052-59. doi: 10.1001/jama.2020.6775
- Grasselli G, Zangrillo A, Zanella A, et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA. 2020;323(16):1574-81. doi: 10.1001/jama.2020.5394
- Shi S, Qin M, Shen B, et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802-10. doi: 10.1001/jamacardio.2020.0950
- Naeini MB, Sahebi M, Nikbakht F, et al. A meta-meta-analysis: Evaluation of meta-analyses published in the effectiveness of cardiovascular comorbidities on the severity of COVID-19. Obes Med. 2021;22:100323. doi: 10.1016/j.obmed.2021.100323
- Casas-Rojo JM, Antón-Santos JM, Millán-Núñez-Cortés J, et al. Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Registry [Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del Registro SEMI-COVID-19] [published online ahead of print, 2020 Sep 9]. Rev Clin Esp (Barc). 2020;220(8):480-94. doi: 10.1016/j.rceng.2020.07.003
- Docherty AB, Harrison EM, Green CA, et al. Features of 20 133 UK patients in hospital with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ. 2020;369:m1985. doi: 10.1136/bmj.m198
- Ssentongo P, Ssentongo AE, Heilbrunn ES, et al. Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis. PLoS One. 2020;15(8):e0238215. doi: 10.1371/journal.pone.0238215
- O'Hearn M, Liu J, Cudhea F, et al. Coronavirus Disease 2019 Hospitalizations Attributable to Cardiometabolic Conditions in the United States: A Comparative Risk Assessment Analysis. Am Heart Assoc. 2021;10(5):e019259. doi: 10.1161/JAHA.120.019259
- Li J, He X, Yuan Yuan, et al. Meta-analysis investigating the relationship between clinical features, outcomes, and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. Am J Infect Control. 2021;49(1):82-9. doi: 10.1016/j.ajic.2020.06.008
- Karagiannidis C, Mostert C, Hentschker C, et al. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. Lancet Respir Med. 2020;8(9):853-62. doi: 10.1016/S2213-2600(20)30316-7
- Yang J, Zheng Y, Gou X, et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis. 2020;94:91-5. doi: 10.1016/j.ijid.2020.03.017
- Parohan M, Yaghoubi S, Seraji A, et al. Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies. Aging Male. 2020;8:1-9. doi: 10.1080/13685538.2020.1774748
- Noor FM, Islam MM. Prevalence and Associated Risk Factors of Mortality Among COVID-19 Patients: A Meta-Analysis. J Community Health. 2020;12. doi: 10.1007/s10900-020-00920-x
- Арутюнов Г.П., Тарловская Е.И., Арутюнов А.Г., и др. Международный регистр «Анализ динамики Коморбидных заболеваний у пациенТов, перенесшИх инфицироВание SARS-CoV-2» (AКТИВ SARS-CoV-2): анализ предикторов неблагоприятных исходов острой стадии новой коронавирусной инфекции. Российский кардиологический журнал. 2021;26(4):116-31 [Arutyunov GP, Tarlovskaya EI, Arutyunov AG, et al. International register “Dynamics analysis of comorbidities in SARS-CoV-2 survivors” (AСTIV SARS-CoV-2): analysis of predictors of short-term adverse outcomes in COVID-19. Russian Journal of Cardiology. 2021;26(4):116-31 (in Russian)]. doi: 10.15829/1560-4071-2021-4470
- Lee ES, Koh HL, Ho EQ, et al. Systematic review on the instruments used for measuring the association of the level of multimorbidity and clinically important outcomes. BMJ Open. 2021;11(5):e041219. doi: 10.1136/bmjopen-2020-041219
- Charlson ME, Pompei P, Ales KL. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. Chron Dis. 1987;40:373-83. doi: 10.1016/0021-9681(87)90171-8
- Самородская И.В., Никифорова М.А. Терминология и методы оценки влияния коморбидности на прогноз и исходы лечения. Бюллетень НЦССХ им. А.Н. Бакулева РАМН. 2013;14(4):18-26. Режим доступа: https://cvdru-journal.com/catalog/detail.php?SECTION_ID=757&ID=18104. Ссылка активна на 02.06.2021 [Samorodskaya I, Nikiforova M. Terminology and methods for assessing the impact of comorbidity on the prognosis and treatment results. The Bulletin of Bakoulev Center Cardiovascular Diseases. 2013;14(4):18-26. Available at: https://cvdru-journal.com/catalog/detail.php?SECTION_ID=757&ID=18104. Accessed: 02.06.2021 (in Russian)].
- Charlson Comorbidity Index (CCI). Available at: https://www.mdcalc.com/ charlson-comorbidity-index-cci. Accessed: 02.06.2021.
- Available at: https: www.epicentro.iss.it/coronavirus/bottettino/Report-COVID-2-19_marzo-v2.pdf. Accessed: 02.06.2021.
- Garg S, Kim L, Whitaker M, et al. Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 - COVID-NET, 14 States, March 1–30, 2020. MMWR. MMWR Morb Mortal Wkly Rep. 2020;69(15):458-64. doi: 10.15585/mmwr.mm6915e3
- Wei X, Zeng W, Su J, et al. Hypolipidemia is associated with the severity of COVID-19. J Clin Lipidol. 2020;14(3):297-304. doi: 10.1016/j.jacl.2020.04.008
- Zhao M, Luo Z, He H, et al. Decreased Low-Density Lipoprotein Cholesterol Level Indicates Poor Prognosis of Severe and Critical COVID-19 Patients: A Retrospective, Single-Center Study. Front Med (Lausanne). 2021;8:585851. doi: 10.3389/fmed.2021.585851
- Zhu L, She ZG, Cheng X, et al. Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes. Cell Metab. 2020;31(6):1068-77.e3. doi: 10.1016/j.cmet.2020.04.021
- Zhu B, Jin S, Wu L, et al. J-shaped association between fasting blood glucose levels and COVID-19 severity in patients without diabetes. Diabetes Res Clin Pract. 2020;168:108381. doi: 10.1016/j.diabres.2020.108381
- Kim DH, Park HC, Cho A, et al. Age-adjusted Charlson comorbidity index score is the best predictor for severe clinical outcome in the hospitalized patients with COVID-19 infection. Medicine (Baltimore). 2021;100(18):e25900. doi: 10.1097/MD.0000000000025900
- Kraemer HC. Statistical issues in assessing comorbidity. Stat Med. 1995;14:721-23.
- Van den Akker M, Buntinx F, Roos S, Knottnerus J.A. Comorbidity or multimorbidity: what's in a name? A review of the literature. Eur J Gen Pract. 1996;2:65-70. doi: 10.3109/13814789609162146
- Van den Akker M, Buntinx F, Metsemakers JF, et al. Multimorbidity in general practice: prevalence, incidence, and determinants of co-occurring chronic and recurrent diseases. J Clin Epidemiol. 1998;51(5):367-75. doi: 10.1016/s0895-4356(97)00306-5
- Арутюнов Г.П., Тарловская Е.И., Арутюнов А.Г., и др. Международный регистр «Анализ динамики Коморбидных заболеваний у пациенТов, перенесшИх инфицироВание SARSCoV-2» (AКТИВ) и регистр «Анализ госпитализаций Коморбидных пациенТов, ИнфицироВанных в период второй волны SARS-CoV-2» (AКТИВ 2). Российский кардиологический журнал. 2021;26(3):4358 [Arutyunov GP, Tarlovskaya EI, Arutyunov AG, et al. International register “Dynamics analysis of comorbidities in SARS-CoV-2 survivors” (AСTIV) and the register “Analysis of hospitalizations of comorbid patients infected during the second wave of SARS-CoV-2 outbreak” (AСTIV 2). Russian Journal of Cardiology. 2021;26(3):4358 (in Russian)]. doi: 10.15829/1560-4071-2021-4358
- Арутюнов Г.П., Тарловская Е.И., Арутюнов А.Г., и др. Международный регистр «Анализ динамики коморбидных заболеваний у пациентов, перенесших инфицирование SARS-CoV-2 (АКТИВ SARS-CoV-2)». Кардиология. 2020;60(11):31-4 [Arutyunov GP, Tarlovskaya EI, Arutyunov AG, et al. International register “Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients (ACTIV SARS-CoV-2)”. Kardiologiia. 2020;60(11):31-4 (in Russian)]. doi: 10.18087/cardio.2020.11.n1398
Supplementary files
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