Locomotive syndrome: from paradigms to clinical reality

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Abstract

Locomotive syndrome is an unsatisfactory condition of patients over 60 years of age who need or may require outside help in the near future due to functional deterioration of the musculoskeletal system, including pathology of bone tissue, joints, muscles and nervous tissue. In real clinical practice, one often has to deal with the following manifestations of locomotive syndrome: osteoarthritis, sarcopenia, balance disorders, chronic musculoskeletal pain. Today, there is a clear understanding that drug therapy should be long-term, include comprehensive support for muscle tissue, balance training, and mandatory cognitive-behavioral therapy. Maximum safety of long-term drug therapy can be ensured by the use of vital micronutrients, which include highly purified forms of chondroitin sulfate and glucosamine sulfate, which have a wide range of anti-inflammatory and regenerative effects.

About the authors

Marina V. Putilina

Pirogov Russian National Research Medical University

Author for correspondence.
Email: profput@mail.ru
ORCID iD: 0000-0002-8655-8501

д-р мед. наук, проф., проф. каф. клинической фармакологии лечебного фак-та

Russian Federation, Moscow

Natalia V. Teplova

Pirogov Russian National Research Medical University

Email: profput@mail.ru
ORCID iD: 0000-0002-7181-4680

д-р мед. наук, проф., зав. каф. клинической фармакологии лечебного фак-та

Russian Federation, Moscow

Aleksander M. Lila

Nasonova Research Institute of Rheumatology;
Russian Medical Academy of Continuous Professional Education

Email: profput@mail.ru
ORCID iD: 0000-0002-6068-3080

чл.-кор. РАН, д-р мед. наук, проф., рук. клиники эндопротезирования суставов ФГБУ «НМИЦ ТО им. Н.Н. Приорова» зав. каф. травматологии и ортопедии ФГАОУ ВО РУДН

Russian Federation, Moscow; Moscow

Nikolay V. Zagorodniy

Research Center of Traumatology and Orthopedics; People’s Friendship University of Russia

Email: profput@mail.ru

чл.-кор. РАН, д-р мед. наук, проф., рук. клиники эндопротезирования суставов ФГБУ «НМИЦ ТО им. Н.Н. Приорова» зав. каф. травматологии и ортопедии ФГАОУ ВО РУДН

Russian Federation, Moscow; Moscow

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