Evaluation of topical therapy of patients with osteoarthritis of small joints of the hands with Voltaren® Emulgel® 2% (diclofenac diethylamine 2%)
- Authors: Tsurko V.V.1,2, Gromova M.A.1
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Affiliations:
- Pirogov Russian National Research Medical University
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 93, No 5 (2021)
- Pages: 599–604
- Section: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/71515
- DOI: https://doi.org/10.26442/00403660.2021.05.200846
- ID: 71515
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Abstract
Aim. To evaluate the efficacy and safety of using the drug Voltaren® Emulgel® 2% (diclofenac diethylaminе 2%) for 14 days in patients with osteoarthritis (OA) of small joints of the hands.
Materials and methods. 62 patients of both sexes with hands OA were included in the study, 31 of whom (main group) used Voltaren® Emulgel® 2% (diclofenac diethylaminе 2%) topically, and the remaining 31 (comparison group) – Voltaren® Emulgel® 2% (diclofenac diethylamine 2%) + oral nonsteroidal anti-inflammatory drugs. The effectiveness of therapy was assessed by using a visual analogue scale (VAS) in dynamics: joint pain and stiffness at rest, pain on movement and during palpation, by functional indices AUSCAN, FIHOA, by assessment of the effect of therapy by the doctor and the patient on a weekly basis.
Results and discussion. Joint pain decreased after 2 weeks of therapy in all patients during treatment with Voltaren® Emulgel® 2% (diclofenac diethylamine 2%) in both groups. Significant reduction in stiffness and improvement in hand joint function was achieved after 7 days and lasted until the end of treatment. By the end of treatment, 100% of patients assessed their condition as improvement.
Conclusion. Voltaren® Emulgel® 2% (diclofenac diethylamine 2%) demonstrates comparable clinical efficacy in patients with OA of the hand joints (reduced pain, stiffness and improved joint function) in monotherapy as complex therapy in combination with oral NSAIDS, while being well tolerated.
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##article.viewOnOriginalSite##About the authors
Vladimir V. Tsurko
Pirogov Russian National Research Medical University; Sechenov First Moscow State Medical University (Sechenov University)
Email: margarita-gromov@mail.ru
ORCID iD: 0000-0001-8040-3704
д-р мед. наук, проф. каф. факультетской терапии лечебного фак-та ФГАОУ ВО «РНИМУ им. Н.И. Пирогова», проф. каф. общей врачебной практики ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова»
Russian Federation, Moscow; MoscowMargarita A. Gromova
Pirogov Russian National Research Medical University
Author for correspondence.
Email: margarita-gromov@mail.ru
ORCID iD: 0000-0002-3757-058X
канд. мед. наук, ассистент каф. факультетской терапии лечебного фак-та
Russian Federation, MoscowReferences
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