Email this article Peculiarities of sonoelastographic imaging of thyroid papillary cancer in presence of autoimmune thyroiditis
- Authors: Khachatryan A.R.1, Vardanyan G.J.2, Avetisyan G.A.2, Chomoyan A.S.3, Baghdasaryan S.E.2, Porksheyan K.A.2
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Affiliations:
- Medical Center “Dialab”
- Mkhitar Heratsi Yerevan State Medical University
- Medical Center “Nairi”
- Issue: Vol 93, No 4 (2021)
- Pages: 369-375
- Section: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/71158
- DOI: https://doi.org/10.26442/00403660.2021.04.200675
- ID: 71158
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Abstract
Aim. To determine the features of visualization of papillar thyroid cancer (PTC) in presence of autoimmune thyroiditis (AIT) according to sonoelastography data.
Materials and methods. 155 patients were examined (75 – PTC, 30 – AIT, 20 – PTC in presence of AIT and 30 – with diffuse parenchymal changes) and 30 patients of the control group. Among patients with PTC 68 (90.7%) were represented by female (mean age 46.7±13.12 years) and 7 (9.3%) – by male (average age – 48.1±4.05 years) patients, PTC in presence of AIT – by 19 female (average age 46.9±16.98 years) and 1 male (22 years) patients. Ultrasound investigation was performed with devices Toshiba Aplio-400 and Toshiba Aplio-500 (Japan) by the standard method and using elastography. A surface transducer with a frequency of 10–14 MHz was used. An analysis of the thyroid ultrasound image was performed in correspondence with TI-RADS. For a qualitative assessment of the elastographic picture of thyroid foci, the Tsukuba–Ueno assessment visual standardized system was implemented.
Results. According to the TI-RADS scale, most nodular formations are assigned to category 4. With TPC with an unchanged thyroid gland, category 4 was determined in 52 patients (69.3%), and with PR in presence of AIT – 15 patients (75%). When determining the qualitative criteria for Tsukuba – Ueno, the majority of tumors were assigned to types 3b and 4: cancers in presence of AIT – 95% and cancers with no changes to thyroid gland – 81.3%. Sonoelastographic criteria for thyroid parenchyma with AIT with a high degree of confidence are significantly higher than in the control group (p<0.000). In a comparative analysis of thyroid sonoelastography in PTC with unchanged parenchyma and AIT, changes according to compression elastography are statistically unreliable. In shear wave elastography, sonoelastographic criteria for PTC are significantly higher in patients with AIT (p<0.02 when measured in kPa, p<0.01 when measured in m/s).
Conclusion. Sonoelastography data can be used as additional criteria in the differential diagnosis of focal thyroid formations.
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##article.viewOnOriginalSite##About the authors
Anna R. Khachatryan
Medical Center “Dialab”
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0003-1865-4144
врач-радиолог МЦ «Диалаб»
Armenia, YerevanGoar J. Vardanyan
Mkhitar Heratsi Yerevan State Medical University
Author for correspondence.
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0002-1972-5373
д.м.н., проф. каф. лучевой диагностики ЕГМУ им. М. Гераци
Armenia, YerevanGarnik A. Avetisyan
Mkhitar Heratsi Yerevan State Medical University
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0001-8745-0060
к.м.н., доц., проректор по постдипломному и непрерывному образованию, зав. каф. лучевой диагностики ЕГМУ им. М. Гераци
Armenia, YerevanAram S. Chomoyan
Medical Center “Nairi”
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0001-9425-6733
эндокринный хирург
Armenia, YerevanSatenik E. Baghdasaryan
Mkhitar Heratsi Yerevan State Medical University
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0002-2632-9416
к.м.н., доц., рук. центра постдипломного и непрерывного образования, доц. каф. эндокринологии ЕГМУ им. М. Гераци
Armenia, YerevanKristina A. Porksheyan
Mkhitar Heratsi Yerevan State Medical University
Email: g.vardanyan11@mail.ru
ORCID iD: 0000-0002-7227-0320
к.м.н., преподаватель каф. лучевой диагностики ЕГМУ им. М. Гераци
Armenia, YerevanReferences
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