Evaluation of the clinical efficacy of local antibacterial therapy in the treatment of acute bacterial rhinosinusitis
- Authors: Banashek-Meshcheriakova T.V.1, Semyonov F.V.1
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Affiliations:
- Kuban State Medical University
- Issue: Vol 92, No 12 (2020)
- Pages: 155-159
- Section: Articles
- URL: https://journals.rcsi.science/0040-3660/article/view/60286
- DOI: https://doi.org/10.26442/00403660.2020.12.000834
- ID: 60286
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Abstract
Aim. To evaluate the clinical efficacy of Polydexa with phenylephrinum in the complex treatment of moderate acute bacterial rhinosinusitis.
Materials and methods. The article presents the results of a clinical study of 100 patients with moderate acute bacterial rhinosinusitis – 37 (37%) men, 63 (63%) women aged 15 to 53 years. The patients were randomized into 2 groups of 50 people each. In the study group, patients received systemic antibiotic therapy and a topical nasal spray of Polydexa with phenylephrinum. The control group received systemic antibacterial therapy and long-acting local decongestants. The evaluation criteria were statistically significant differences in clinical and laboratory parameters of the control and main groups.
Results and conclusion. The pronounced anti-inflammatory, antimicrobial effects of the drug were confirmed; conclusions were drawn about the clinical efficacy, tolerability, safety of Polydexa with phenylephrinum and allows to achieve complete resolution of the pathological process in more cases.
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##article.viewOnOriginalSite##About the authors
T. V. Banashek-Meshcheriakova
Kuban State Medical University
Author for correspondence.
Email: banashek@mail.ru
ORCID iD: 0000-0003-2317-4794
к.м.н., ассистент
Russian Federation, KrasnodarF. V. Semyonov
Kuban State Medical University
Email: banashek@mail.ru
ORCID iD: 0000-0002-4323-9869
д.м.н., проф., зав. каф
Russian Federation, KrasnodarReferences
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