Email this article POEMS-syndrome: diagnostic difficulties
- Authors: Lebedev P.A.1, Paranina E.V.1, Rossiyev V.A.2, Fedorova E.Y.2, Nikolaeva A.S.2
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Affiliations:
- Samara State Medical University
- Seredavin Samara Regional Clinical Hospital
- Issue: Vol 92, No 7 (2020)
- Pages: 104-108
- Section: Clinical notes
- URL: https://journals.rcsi.science/0040-3660/article/view/43134
- DOI: https://doi.org/10.26442/00403660.2020.07.000596
- ID: 43134
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Abstract
POEMS – syndrome is a rare paraneoplastic syndrome whose name is an acronym formed from the initial letters of the names of the symptoms originally used to determine it: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. Due to the rarity of the disease and the small number of cases described in the literature, its diagnosis is difficult. The average time from onset of symptoms to diagnosis is 18 months. Moreover, the prognosis of the disease depends on the early onset of specific treatment. The article describes a clinical case of POEMS-syndrome in a 53-year-old man, which illustrates the difficulties associated with the timely recognition of this unusual disease.
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##article.viewOnOriginalSite##About the authors
P. A. Lebedev
Samara State Medical University
Email: eles77@list.ru
ORCID iD: 0000-0003-1404-7099
д.м.н., проф., зав. каф. терапии Института профессионального образования ФГБОУ ВО СамГМУ
Russian Federation, SamaraE. V. Paranina
Samara State Medical University
Author for correspondence.
Email: eles77@list.ru
ORCID iD: 0000-0001-7021-4061
к.м.н., доц., каф. терапии Института профессионального образования ФГБОУ ВО СамГМУ
Russian Federation, SamaraV. A. Rossiyev
Seredavin Samara Regional Clinical Hospital
Email: eles77@list.ru
к.м.н., зав. гематологическим отд-нием по 23.12.2019, врач-гематолог ГБУЗ «СОКБ им. В.Д. Середавина»
Russian Federation, SamaraE. Y. Fedorova
Seredavin Samara Regional Clinical Hospital
Email: eles77@list.ru
врач-гематолог гематологического отд-ния ГБУЗ «СОКБ им. В.Д. Середавина»
Russian Federation, SamaraA. S. Nikolaeva
Seredavin Samara Regional Clinical Hospital
Email: eles77@list.ru
зав. гематологическим отд-нием, врач-гематолог гематологического отд-ния ГБУЗ «СОКБ им. В.Д. Середавина»
Russian Federation, SamaraReferences
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